catalog number :
MBS2602697
products type :
ELISA Kit
products full name :
Human Calcitonin gene-related peptide 2 (CALCB) ELISA Kit
products short name :
Calcitonin gene-related peptide 2 (CALCB)
other names :
calcitonin gene-related peptide 2; Calcitonin gene-related peptide 2; calcitonin gene-related peptide 2; beta-CGRP; calcitonin 2; beta-type CGRP; calcitonin gene-related peptide II; calcitonin-related polypeptide beta; Beta-type CGRP; Beta-CGRP; Calcitonin gene-related peptide II
products gene name :
CALCB
other gene names :
CALCB; CALCB; CALC2; CGRP2; CGRP-II; CALC2; Beta-CGRP; CGRP-II
uniprot entry name :
CALCB_HUMAN
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant CALCB concentration. Assay Type: Sandwich. Detection Range: 10 ng/ml-0.156 ng/ml. Sensitivity: 0.05 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human CALCB monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi acc num :
NP_000719.1
ncbi gb acc num :
NM_000728.3
ncbi mol weight :
13,706 Da
ncbi pathways :
Calcitonin-like Ligand Receptors Pathway (106379); Class B/2 (Secretin Family Receptors) Pathway (106378); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
uniprot summary :
CALCB: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. Belongs to the calcitonin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11p15.2-p15.1. Cellular Component: extracellular region. Molecular Function: neuropeptide hormone activity. Biological Process: cellular calcium ion homeostasis; signal transduction