product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human CTP synthase 2, CTPS2 ELISA Kit
catalog :
MBS2602678
quantity :
48-Strip-Wells
price :
275 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602678
products type :
ELISA Kit
products full name :
Human CTP synthase 2, CTPS2 ELISA Kit
products short name :
CTP synthase 2, CTPS2
other names :
CTP synthase 2; CTP synthase 2; CTP synthase 2; CTP synthase II; UTP-ammonia ligase 2; CTP synthetase type 2; cytidine 5'-triphosphate synthetase 2; CTP synthase 2; CTP synthetase 2; UTP--ammonia ligase 2
products gene name :
CTPS2
other gene names :
CTPS2; CTPS2
uniprot entry name :
PYRG2_HUMAN
reactivity :
Human
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant CTPS2 concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Priciple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human CTPS2 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
221316689
ncbi acc num :
NP_001137474.1
ncbi gb acc num :
NM_001144002.1
uniprot acc num :
Q9NRF8
ncbi mol weight :
65,678 Da
ncbi pathways :
Metabolism Pathway (477135); Metabolism Of Nucleotides Pathway (106263); Pyrimidine Metabolism Pathway (82946); Pyrimidine Metabolism Pathway (309); Pyrimidine Ribonucleotide Biosynthesis, UMP = UDP/UTP,CDP/CTP Pathway (413360); Pyrimidine Ribonucleotide Biosynthesis, UMP = UDP/UTP,CDP/CTP Pathway (468245); Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway (161057); Pyrimidine Ribonucleotides De Novo Biosynthesis Pathway (142283); Pyrimidine Ribonucleotides Interconversion Pathway (142282); Pyrimidine Ribonucleotides Interconversion Pathway (138648)
ncbi summary :
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
uniprot summary :
CTPS2: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. Belongs to the CTP synthase family. Protein type: Nucleotide Metabolism - pyrimidine; EC 6.3.4.2; Ligase. Chromosomal Location of Human Ortholog: Xp22. Cellular Component: mitochondrion; cytosol. Molecular Function: CTP synthase activity; ATP binding. Biological Process: nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; pyrimidine nucleotide metabolic process; glutamine metabolic process
size1 :
48-Strip-Wells
price1 :
275 USD
size2 :
96-Strip-Wells
price2 :
420
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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