product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A autoantibody ELISA Kit
catalog :
MBS2602668
quantity :
48-Strip-Wells
price :
275 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602668
products type :
ELISA Kit
products full name :
Human high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A autoantibody ELISA Kit
products short name :
high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A autoantibody
other names :
high affinity immunoglobulin epsilon receptor subunit alpha; High affinity immunoglobulin epsilon receptor subunit alpha; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypeptide; high affinity immunoglobulin epsilon receptor alpha-subunit; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha
products gene name :
FCER1A
other gene names :
FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI
uniprot entry name :
FCERA_HUMAN
reactivity :
Human
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or cell culture supernatant and organizations in the natural and recombinant FCER1A Ab concentration. Assay Type: Sandwich. Detection Range: 100 U/ml-1.56 U/ml. Sensitivity: 0.5 U/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Principle of the Assay This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human FCER1A Ab monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
4503675
ncbi acc num :
NP_001992.1
ncbi gb acc num :
NM_002001.3
uniprot acc num :
P12319
ncbi mol weight :
29,596 Da
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532); Fc Epsilon RI Signaling Pathway (83082); Fc Epsilon RI Signaling Pathway (493); Fc Epsilon Receptor (FCERI) Signaling Pathway (833825); Fc-epsilon Receptor I Signaling In Mast Cells Pathway (138050); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
uniprot summary :
Function: Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
size1 :
48-Strip-Wells
price1 :
275 USD
size2 :
96-Strip-Wells
price2 :
420
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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