product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Small ubiquitin-related modifier 4, SUMO4 ELISA Kit
catalog :
MBS2602644
quantity :
48-Strip-Wells
price :
275 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2602644
products type :
ELISA Kit
products full name :
Human Small ubiquitin-related modifier 4, SUMO4 ELISA Kit
products short name :
Small ubiquitin-related modifier 4, SUMO4
other names :
small ubiquitin-related modifier 4; Small ubiquitin-related modifier 4; small ubiquitin-related modifier 4; insulin-dependent diabetes mellitus 5; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 4; small ubiquitin-like modifier 4 protein; small ubiquitin-like modifier 4; Small ubiquitin-like protein 4
products gene name :
SUMO4
other gene names :
SUMO4; SUMO4; IDDM5; SMT3H4; SUMO-4; dJ281H8.4; SMT3H4; SUMO-4
uniprot entry name :
SUMO4_HUMAN
reactivity :
Human
specificity :
No cross-reaction with other factors.
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant SUMO4 concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.
other info2 :
Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%
products description :
Priciple of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human SUMO4 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
ncbi gi num :
50400081
ncbi acc num :
NP_001002255.1
ncbi gb acc num :
NM_001002255.1
uniprot acc num :
Q6EEV6
ncbi mol weight :
10,685 Da
ncbi pathways :
Nuclear Pore Complex Pathway (470351); RNA Transport Pathway (177876); RNA Transport Pathway (175229)
ncbi summary :
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008]
uniprot summary :
SUMO4: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. Belongs to the ubiquitin family. SUMO subfamily. Protein type: Ubiquitin-like modifier. Chromosomal Location of Human Ortholog: 6q25. Cellular Component: nucleus. Biological Process: protein sumoylation. Disease: Diabetes Mellitus, Insulin-dependent, 5
size1 :
48-Strip-Wells
price1 :
275 USD
size2 :
96-Strip-Wells
price2 :
420
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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