Rabbit Calcitonin Gene Related Peptide (CGRP) ELISA KIT | MyBioSource MBS2602448 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rabbit Calcitonin Gene Related Peptide (CGRP) ELISA KIT

catalog :

MBS2602448

quantity :

48-Strip-Wells

price :

275 USD

product information

catalog number :

MBS2602448

products type :

ELISA Kit

products full name :

Rabbit Calcitonin Gene Related Peptide (CGRP) ELISA KIT

products short name :

[Calcitonin Gene Related Peptide (CGRP)]

other names :

[calcitonin gene-related peptide 1 isoform alpha-CGRP preproprotein; Calcitonin gene-related peptide 1; calcitonin; calcitonin gene-related peptide 1; katacalcin; calcitonin 1; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; calcitonin-related polypeptide alpha; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I]

products gene name :

[CGRP]

other gene names :

[CALCA; CALCA; CT; KC; CGRP; CALC1; CGRP1; CGRP-I; CALC1; CGRP-I]

uniprot entry name :

CALCA_HUMAN

reactivity :

Rabbit

sequence length :

128

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

image1 heading :

Typical Standard Curve/Testing Data

other info1 :

Samples: Serum, plasma or cell culture supernatant. Assay Type: Quantitative Sandwich. Detection Range: 1000 pg/ml-15.6 pg/ml. Sensitivity: Up to 5 pg/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Rabbit CGRP monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

76880478

ncbi acc num :

NP_001029125.1

ncbi gb acc num :

NM_001033953.2

ncbi mol weight :

15,466 Da

ncbi pathways :

Amyloids Pathway (366238); Calcitonin-like Ligand Receptors Pathway (106379); Class B/2 (Secretin Family Receptors) Pathway (106378); Disease Pathway (530764); Endothelin Pathway (672453); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Myometrial Relaxation And Contraction Pathways (198759); Signal Transduction Pathway (477114)

ncbi summary :

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]

uniprot summary :

CALCA iso3: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11p15.2. Cellular Component: extracellular space; cell soma; cytoplasm; extracellular region; terminal button; nucleus. Molecular Function: identical protein binding; protein binding; calcitonin receptor binding; hormone activity; protein complex binding; receptor binding. Biological Process: negative regulation of osteoclast differentiation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of interleukin-1 alpha production; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure; response to pain; positive regulation of vasodilation; protein amino acid phosphorylation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of interleukin-8 production; monocyte chemotaxis; elevation of cytosolic calcium ion concentration; leukocyte adhesion; vasculature development; cell-cell signaling; neuropeptide signaling pathway; regulation of blood pressure; negative regulation of smooth muscle contraction; receptor internalization; positive regulation of cAMP biosynthetic process; negative regulation of ossification; feeding behavior; negative regulation of blood pressure; positive regulation of adenylate cyclase activity; negative regulation of bone resorption; detection of temperature stimulus involved in sensory perception of pain; inflammatory response; positive regulation of macrophage differentiation; negative regulation of neurological process; aging; cytosolic calcium ion homeostasis; regulation of heart rate; adenylate cyclase activation; positive regulation of ossification; regulation of systemic arterial blood pressure by neurological process; G-protein coupled receptor internalization; response to heat; endothelial cell proliferation; regulation of inflammatory response; activation of protein kinase activity; endothelial cell migration; negative regulation of transcription, DNA-dependent; embryo implantation

size1 :

48-Strip-Wells

price1 :

275 USD

size2 :

96-Strip-Wells

price2 :

435

size3 :

5x96-Strip-Wells

price3 :

1755

size4 :

10x96-Strip-Wells

price4 :

3150