Rabbit Parathyroid Hormone (PTH) ELISA Kit | MyBioSource MBS2601136 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rabbit Parathyroid Hormone (PTH) ELISA Kit

catalog :

MBS2601136

quantity :

48-Strip-Wells

price :

315 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2601136

products type :

ELISA Kit

products full name :

Rabbit Parathyroid Hormone (PTH) ELISA Kit

products short name :

Parathyroid Hormone (PTH)

other names :

parathyroid hormone preproprotein; Parathyroid hormone; parathyroid hormone; parathyrin; prepro-PTH; parathormone; parathyroid hormone 1; preproparathyroid hormone; parathyroid hormone; Parathormone; Parathyrin

products gene name :

PTH

other gene names :

PTH; PTH; PTH1; PTH

uniprot entry name :

PTHY_HUMAN

reactivity :

Rabbit

sequence length :

115

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Rabbit serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant PTH concentration. Assay Type: Sandwich. Detection Range: 1000 pg/ml-15.6 pg/ml. Sensitivity: 5 pg/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Rabbit PTH monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

4506267

ncbi acc num :

NP_000306.1

ncbi gb acc num :

NM_000315.2

ncbi mol weight :

12,861 Da

ncbi pathways :

Class B/2 (Secretin Family Receptors) Pathway (106378); Endochondral Ossification Pathway (198812); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Osteoblast Signaling Pathway (198842); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); Vitamin D Synthesis Pathway (198764)

ncbi summary :

The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008]

uniprot summary :

PTH: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Belongs to the parathyroid hormone family. Protein type: Apoptosis; Hormone; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11p15.3-p15.1. Cellular Component: extracellular space; extracellular region. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; type 1 parathyroid hormone receptor binding; parathyroid hormone receptor binding; peptide hormone receptor binding; hormone activity. Biological Process: transcription from RNA polymerase II promoter; response to drug; positive regulation of signal transduction; induction of apoptosis by hormones; positive regulation of glycogen biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of bone mineralization; G-protein signaling, adenylate cyclase activating pathway; Rho protein signal transduction; cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway; positive regulation of glucose import; cAMP metabolic process; response to ethanol; response to vitamin D; response to cadmium ion; cell-cell signaling; regulation of gene expression; positive regulation of cAMP biosynthetic process; response to lead ion; positive regulation of transcription from RNA polymerase II promoter; skeletal development; bone resorption. Disease: Hypoparathyroidism, Familial Isolated

size1 :

48-Strip-Wells

price1 :

315 USD

size2 :

96-Strip-Wells

price2 :

490

more info or order :

MyBioSource product webpage