ELISA/assay

Mouse Adrenocorticotropic Hormone (ACTH) ELISA Kit

MBS260108

48-Strip-Wells

290 USD

ELISA Kit

Mouse Adrenocorticotropic Hormone (ACTH) ELISA Kit

Adrenocorticotropic Hormone (ACTH)

adrenocorticotropic hormone, partial; Pro-opiomelanocortin; pro-opiomelanocortin; beta-endorphin; met-enkephalin; melanotropin gamma; corticotropin-lipotropin; adrenocorticotropic hormone; adrenal corticotropic hormone; alpha-melanocyte stimulating hormone; corticotropin-like intermediary peptide; pro-opiomelanocortin-alpha; Corticotropin-lipotropinCleaved into the following 10 chains:NPP; Melanotropin gammaAlternative name(s):Gamma-MSH

ACTH

Pomc; Pomc; BE; Npp; ACTH; Clip; Pomc1; Pomc-1; Beta-LPH; alphaMSH; beta-MSH; Gamma-LPH; alpha-MSH; gamma-MSH; Pomc1; POMC; ACTH; CLIP

COLI_MOUSE

Mouse

39

Store all reagents at 2-8 degree C.

Samples: Mouse serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant ACTH concentration. Assay Type: Sandwich. Detection Range: 1000 pg/ml-15.6 pg/ml

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Mouse ACTH monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

191659

AAA37169.1

26,707 Da

Adipocytokine Signaling Pathway (83290); Adipocytokine Signaling Pathway (505); Androgen Biosynthesis Pathway (1001065); Biological Oxidations Pathway (970688); Class A/1 (Rhodopsin-like Receptors) Pathway (1000942); Cytochrome P450 - Arranged By Substrate Type Pathway (971395); Endogenous Sterols Pathway (1001152); G Alpha (i) Signalling Events Pathway (1000973); G Alpha (s) Signalling Events Pathway (1000972); G-protein Activation Pathway (1000983)

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of this gene is associated with obesity, defects in adrenal development, and altered pigmentation. A pseudogene of this gene is located on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

POMC: ACTH stimulates the adrenal glands to release cortisol. Defects in POMC may be associated with susceptibility to obesity (OBESITY). It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. Defects in POMC are the cause of pro-opiomelanocortinin deficiency (POMCD). Affected individuals present early-onset obesity, adrenal insufficiency and red hair. Belongs to the POMC family. Protein type: Secreted; Secreted, signal peptide. Cellular Component: peroxisomal matrix; extracellular space; cytoplasm; extracellular region; secretory granule. Molecular Function: type 3 melanocortin receptor binding; G-protein-coupled receptor binding; type 4 melanocortin receptor binding; hormone activity; receptor binding. Biological Process: generation of precursor metabolites and energy; cell-cell signaling; neuropeptide signaling pathway; regulation of blood pressure; regulation of appetite; positive regulation of transcription from RNA polymerase II promoter; negative regulation of tumor necrosis factor production; glucose homeostasis; signal transduction; cellular pigmentation

48-Strip-Wells

290 USD

96-Strip-Wells

450