Human lumican (LUM) ELISA Kit | MyBioSource MBS260082 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human lumican (LUM) ELISA Kit

catalog :

MBS260082

quantity :

48-Strip-Wells

price :

275 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS260082

products type :

ELISA Kit

products full name :

Human lumican (LUM) ELISA Kit

products short name :

lumican (LUM)

other names :

lumican; Lumican; lumican; KSPG lumican; lumican proteoglycan; keratan sulfate proteoglycan lumican; lumican; Keratan sulfate proteoglycan lumican; KSPG lumican

products gene name :

LUM

other gene names :

LUM; LUM; LDC; SLRR2D; LDC; SLRR2D; KSPG lumican

uniprot entry name :

LUM_HUMAN

reactivity :

Human

sequence length :

338

specificity :

No cross-reaction with other factors.

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant LUM concentration. Assay Type: Sandwich. Detection Range: 20 ng/ml-0.312 ng/ml. Sensitivity: 0.06 ng/ml.

other info2 :

Intra-assay Precision: <= 8%. Inter-assay Precision: <= 12%

products description :

Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human LUM monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

ncbi gi num :

4505047

ncbi acc num :

NP_002336.1

ncbi gb acc num :

NM_002345.3

ncbi mol weight :

38,429 Da

ncbi pathways :

Disease Pathway (530764); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); Glycosaminoglycan Metabolism Pathway (645297); Keratan Sulfate Biosynthesis Pathway (645302); Keratan Sulfate Degradation Pathway (645303); Keratan Sulfate/keratin Metabolism Pathway (645301); MPS I - Hurler Syndrome Pathway (685537); MPS II - Hunter Syndrome Pathway (685538); MPS IIIA - Sanfilippo Syndrome A Pathway (685539)

ncbi summary :

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]

uniprot summary :

LUM: a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 12q21.33. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; lysosomal lumen; extracellular space; fibrillar collagen; Golgi lumen; extracellular region. Molecular Function: collagen binding; protein binding; extracellular matrix structural constituent. Biological Process: keratan sulfate metabolic process; extracellular matrix organization and biogenesis; collagen fibril organization; visual perception; glycosaminoglycan metabolic process; cartilage development; keratan sulfate biosynthetic process; carbohydrate metabolic process; pathogenesis; positive regulation of transcription from RNA polymerase II promoter; keratan sulfate catabolic process; response to organic cyclic substance

size1 :

48-Strip-Wells

price1 :

275 USD

size2 :

96-Strip-Wells

price2 :

420

more info or order :

MyBioSource product webpage