product summary
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company name :
MyBioSource
product type :
antibody
product name :
NPHS1 Polyclonal Antibody
catalog :
MBS2556230
quantity :
0.06 mL
price :
150 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
immunohistochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2556230 image 1
Immunohistochemistry analysis of paraffin-embedded mouse kidney using NPHS1 Polyclonal Antibody at dilution of 1:1000.
product information
catalog number :
MBS2556230
products type :
Antibody
products full name :
NPHS1 Polyclonal Antibody
products short name :
[NPHS1]
products name syn :
[CNF; Nephrin; Nephrosis 1 congenital Finnish type; Nephrosis 1; congenital; Finnish type (nephrin); NPHN; NPHN; NPHS 1; Nphs1; Renal glomerulus specific cell adhesion receptor; Renal glomerulus-specific cell adhesion receptor]
other names :
[nephrin; Nephrin; nephrin; nephrosis 1, nephrin; Renal glomerulus-specific cell adhesion receptor]
products gene name :
[NPHS1]
other gene names :
[Nphs1; Nphs1; nephrin; NephrinB; Nphn]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
sequence length :
1,242
purity :
Affinity Purification
form :
PBS with 0.02% sodium azide, 100 ug/ml BSA and 50% glycerol.
storage stability :
Store at -20 degree C. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC)
app notes :
IHC: 1:1000-1:2000
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: KLH conjugated synthetic peptide corresponding to Mouse Nephrin
products categories :
Cancer; Signal Transduction
products description :
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.In Western blots, nephrin antibodies generated against the two terminal extracellular Ig domains of recombinant human nephrin recognized a 180-kDa protein in lysates of human glomeruli and a 150-kDa protein in transfected COS-7 cell lysates.
ncbi gi num :
120586997
ncbi acc num :
NP_062332.2
ncbi gb acc num :
NM_019459.2
uniprot acc num :
Q9QZS7
ncbi pathways :
Cell-Cell Communication Pathway (1366863); Nephrin Interactions Pathway (1366875); PodNet: Protein-protein Interactions In The Podocyte Pathway (755428); Primary Focal Segmental Glomerulosclerosis FSGS Pathway (920872); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)
uniprot summary :
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.
size1 :
0.06 mL
price1 :
150 USD
size2 :
0.12 mL
price2 :
225
size3 :
0.2 mL
price3 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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