product summary
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company name :
MyBioSource
product type :
antibody
product name :
SLC6A4 Polyclonal Antibody
catalog :
MBS2555322
quantity :
0.06 mL
price :
150 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2555322 image 1
Western blot analysis of extracts of various cell lines, using SLC6A4 antibody.
product information
catalog number :
MBS2555322
products type :
Antibody
products full name :
SLC6A4 Polyclonal Antibody
products short name :
[SLC6A4]
products name syn :
[5 HTT; 5 HTTLPR; 5 hydroxytryptamine (serotonin) transporter; 5 hydroxytryptamine transporter; 5HT transporter; 5HTT; hSERT; HTT; Na+/Cl- dependent serotonin transporter; OCD1; SC6A4; Serotonin transporter 1; SERT; SERT1; Slc6a4; Sodium dependent serotonin transporter; Sodium-dependent serotonin transporter; Solute carrier family 6 (neurotransmitter transporter) member 4; solute carrier family 6 (neurotransmitter transporter; serotonin), member 4; Solute carrier family 6 member 4]
other names :
[sodium-dependent serotonin transporter; Sodium-dependent serotonin transporter; sodium-dependent serotonin transporter; solute carrier family 6 member 4; 5HT transporter; 5HTT; Solute carrier family 6 member 4]
products gene name :
[SLC6A4]
other gene names :
[SLC6A4; SLC6A4; HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR; HTT; SERT; SERTBy similarityManual assertion inferred from sequence similarity toiUniProtKB:P31652 (SC6A4_RAT); 5HTT]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
672
purity :
Affinity Purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
storage stability :
Store at -20°C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide of human SLC6A4. Calculated MW: 70kDa/74kDa. Observed MW: 69 kD
other info2 :
Conjugation: Unconjugated
products categories :
Cancer; Metabolism; Neuroscience; Signal Transduction
products description :
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
ncbi gi num :
4507043
ncbi acc num :
NP_001036.1
ncbi gb acc num :
NM_001045.6
uniprot acc num :
P31645
ncbi pathways :
Monoamine Transport Pathway (198851); SIDS Susceptibility Pathways (198901); Serotonergic Synapse Pathway (525336); Synaptic Vesicle Pathway (672457)
ncbi summary :
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
uniprot summary :
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
size1 :
0.06 mL
price1 :
150 USD
size2 :
0.12 mL
price2 :
225
size3 :
0.2 mL
price3 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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