product summary
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company name :
MyBioSource
product type :
antibody
product name :
Purified Anti-Mouse CD49b Monoclonal Antibody
catalog :
MBS2553981
quantity :
0.05 mg
price :
100 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
[DX5]
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2553981
products type :
Antibody
products full name :
Purified Anti-Mouse CD49b Monoclonal Antibody
products short name :
[CD49b]
products name syn :
[Mouse CD49b; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b]
other names :
[Integrin alpha-2; integrin alpha-2; integrin alpha 2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD_antigen: CD49b]
products gene name :
[CD49b]
other gene names :
[Itga2; Itga2; DX5; GPIa; CD49B; GPIa]
clonality :
Monoclonal
isotype :
IgM
clone :
[DX5]
host :
Rat
reactivity :
Mouse
sequence length :
1,178
form :
Liquid; PBS with 0.05% Proclin300
storage stability :
Shipping: Ships at 4 degree C. Stability & Storage: Store at 2-8 degree C and protected from prolonged to light. Do not freeze.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
app notes :
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <=0.25 ug per million cells in 100 ul volume.
other info1 :
Conjugation: Unconjugated
other info2 :
Cellular Localization: Membrane
products description :
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin alpha chain also known as alpha2 integrin, VLA-2 alpha chain, and integrin alpha2 chain. CD49b non-covalently associates with CD29 (beta1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
products references :
1. Arase H, et al. 2001. J. Immunol. 167:1141. 2. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 3. Sasaki K, et al. 2003. Int. Immunol. 15:701. 4. Inoue O, et al. 2003. J. Cell Biol. 160:769.
ncbi acc num :
NP_032422.2
uniprot acc num :
Q62469
ncbi mol weight :
128,955 Da
uniprot summary :
Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis.
size1 :
0.05 mg
price1 :
100 USD
size2 :
0.1 mg
price2 :
115
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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