catalog number :
MBS2553261
products type :
Recombinant Protein
products full name :
Recombinant Human Sulfotransferase/SULT1C4/SULT1C2 Protein
products short name :
[Sulfotransferase/SULT1C4/SULT1C2]
products name syn :
[SULT1C4; Sulfotransferase; SULT1C2; hCG_27301]
other names :
[sulfotransferase 1C4 isoform 2; Sulfotransferase; sulfotransferase 1C4; sulfotransferase family 1C member 4]
products gene name :
[SULT1C4/SULT1C2]
other gene names :
[SULT1C4; SULT1C4; SULT1C; SULT1C2; SULT1C2ImportedAutomatic assertion inferred from database entriesiEMBL:EAW53885.1]
sequence positions :
[Met 1-Lys102]
purity :
> 95 % as determined by reducing SDS-PAGE.
form :
Lyophilized from a 0.2 um filtered solution of 4mM HCl.
storage stability :
Lyophilized proteins are stable for up to 12 months when stored at -20°C to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
image1 heading :
SDS-PAGE
other info1 :
Species: Human. Tag: N-6His
other info2 :
Endotoxin: < 1.0 EU per ug as determined by the LAL method. Reconstitution: Centrifuge tubes before opening. Do not mix by vortex or pipetting. It is recommended that 4mM HCl (50ul) be added to the vial to prepare a stock solution of 0.2mg/mL.
products description :
Human Sulfotransferase (SULT1C4) is an enzyme that in humans is encoded by the SULT1C4 gene, belongs to the sulfotransferase 1 family. SULT1C4 is expressed at high levels in fetal lung and kidney and at low levels in fetal heart, adult kidney, ovary and spinal chord. Sulfotransferase utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. It shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). SULT1C4 plays an important role incatalyzing the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds.
ncbi acc num :
NP_001308699.1
ncbi gb acc num :
NM_001321770.1
ncbi mol weight :
Mol_Mass: 14.1 kDa. AP_Mol_Mass: 14 kDa
ncbi pathways :
Biological Oxidations Pathway (1270189); Cytosolic Sulfonation Of Small Molecules Pathway (1270210); Metabolism Pathway (1269956); Metapathway Biotransformation (198837); Phase II Conjugation Pathway (1270207); Sulfation Biotransformation Reaction Pathway (198899)
ncbi summary :
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. [provided by RefSeq, Jul 2008]