product summary
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company name :
MyBioSource
product type :
antibody
product name :
SLCO1B3 Monoclonal Antibody
catalog :
MBS2549138
quantity :
0.06 mL
price :
220 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[1D9A4]
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2549138 image 1
Western Blot analysis of various cell lines using SLCO1B3 Monoclonal Antibody at dilution of 1:4000.
product information
catalog number :
MBS2549138
products type :
Antibody
products full name :
SLCO1B3 Monoclonal Antibody
products short name :
[SLCO1B3]
products name syn :
[LST 2; LST 3TM13; LST2; LST3; OATP 8; OATP1B3; OATP8; Organic anion transporter 8; SLC21A8; SLCO1B3]
other names :
[Homo sapiens solute carrier organic anion transporter family, member 1B3, mRNA; Solute carrier organic anion transporter family member; solute carrier organic anion transporter family member 1B3; solute carrier organic anion transporter family member 1B3]
products gene name :
[SLCO1B3]
other gene names :
[SLCO1B3; SLCO1B3; LST3; HBLRR; LST-2; OATP8; OATP-8; OATP1B3; SLC21A8; LST-3TM13]
clonality :
Monoclonal
isotype :
IgG1
clone :
[1D9A4]
host :
Mouse
reactivity :
Human
sequence length :
1019
purity :
Protein G Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB: 1:1000-1:10000. IHC: 1:50-1:500
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Fusion Protein of SLCO1B3. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3 . Calculated MW: 702aa;77kDa. Observed MW: 68-77kDa
products description :
SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compoundsincluding bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. The molecular mass of SLCO1B3 is highly dependent on the glycosylation modification (deglycosylated form of 65 kDa, fully-glycosylated form of 120 kDa).
ncbi gi num :
111494039
ncbi acc num :
BC105597
uniprot acc num :
Q0VGL9
ncbi pathways :
Bile Acid And Bile Salt Metabolism Pathway (1270040); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Recycling Of Bile Acids And Salts Pathway (1270045); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Organic Anions Pathway (1269943); Transport Of Vitamins, Nucleosides, And Related Molecules Pathway (1269939)
ncbi summary :
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
size1 :
0.06 mL
price1 :
220 USD
size2 :
0.12 mL
price2 :
290
size3 :
0.2 mL
price3 :
435
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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