catalog number :
MBS254739
products type :
Recombinant Protein
products full name :
Glial Fibrillary Acidic Protein (GFAP)
products short name :
Glial Fibrillary Acidic Protein (GFAP)
other names :
glial fibrillary acidic protein isoform 1; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein; N/A
products gene name :
GFAP
other gene names :
GFAP; GFAP; GFAP
uniprot entry name :
GFAP_HUMAN
sequence :
The target protein is fused with two N-terminal Tags, His-tag and S-tag, its sequence is listed below. MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EFEEWYRSKF ADL TDAAARN AELLRQAKHE ANDYRRQLQS L TCDLESLRG TNESLERQMR EQEERHVREA ASYQEALARL EEEGQSLKDE MARHLQEYQD LLNVKLALDI EIATYRKLLE GEE
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 Degree C for one month. Aliquot and store at -80 Degree C for 12 months. Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 Degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
tested application :
Applications: SOS-PAGE; WB; ELISA; IP. Applications: SOS-PAGE; WB; ELISA; IP. (May be suitable for use in other assays to be determined by the end user.)
other info1 :
Tag Information: two N-terminal Tags, His-tag and S-tag. Residues: Glu254-Glu374 (Accession # P14136), with two N-terminal Tags, His-tag and S-tag. Subcellular Location: Cytoplasm. Endotoxin Level: 5.1. Accurate Molecular Mass: 25kDa as determined by SDS-PAGE reducing conditions.
other info2 :
Organism: Homo sapiens (Human). USAGE: Reconstitute in ddH20.
ncbi acc num :
NP_002046.1
ncbi gb acc num :
NM_002055.4
ncbi mol weight :
20.0kDa
ncbi pathways :
Neural Crest Differentiation Pathway 672460!!Nuclear Signaling By ERBB4 Pathway 530744!!Signal Transduction Pathway 477114!!Signaling By ERBB4 Pathway 530741!!Spinal Cord Injury Pathway 739007
ncbi summary :
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]