catalog number :
MBS2546721
products type :
Recombinant Protein
products full name :
Recombinant Mouse B2M / Beta-2-microglobulin Protein (His tag)
products short name :
[B2M / Beta-2-microglobulin]
products name syn :
[beta2-m; beta2m; Ly-m11]
other names :
[beta-2-microglobulin; Beta-2-microglobulin; beta-2-microglobulin; beta-2 microglobulin]
products gene name :
[B2M]
other gene names :
[B2m; B2m; Ly-m11; beta2m; beta2-m]
purity :
> 97 % as determined by SDS-PAGE
form :
Lyophilized from sterile PBS, pH 7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween80.
storage stability :
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. This product is provided as lyophilized powder which is shipped with ice packs.
image1 heading :
SDS-PAGE
other info1 :
Samples: Tissue Extracts, Cell Lysate, Cell Culture Media And Other Biological Fluids Samples. Detection Range: 0.1 umol/ml-10 umol/ml
products description :
Background/Introduction: ATP synthase (EC 3.6.3.14) is an important enzyme that creates the energy storage molecule adenosine triphosphate (ATP). ATP is the most commonly used "energy currency" of cells for most organisms. It is formed from adenosine diphosphate (ADP) and inorganic phosphate (Pi), and needs energy for its formation. The assay is used to determine Cytochrome C oxidase activity. The enzyme catalysed reaction products Pi can react with dry reagent, and can be measured at a colorimetric readout at 660 nm.
ncbi acc num :
NP_033865.2
ncbi gb acc num :
NM_009735.3
ncbi mol weight :
Molecular Mass: 13 kDa. Actual Protein Molecular Mass: 15 kDa
ncbi pathways :
Adaptive Immune System Pathway (1367473); Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway (1367493); Antigen Processing And Presentation Pathway (83271); Antigen Processing And Presentation Pathway (485); Antigen Processing-Cross Presentation Pathway (1367494); Class I MHC Mediated Antigen Processing Presentation Pathway (1367491); DAP12 Interactions Pathway (1367572); DAP12 Signaling Pathway (1367573); ER-Phagosome Pathway (1367496); Endosomal/Vacuolar Pathway (1367497)
uniprot summary :
B2M: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Heterodimer of an alpha chain and a beta chain. Beta-2- microglobulin is the beta-chain of major histocompatibility complex class I molecules. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. Belongs to the beta-2-microglobulin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2 E5 2 60.55 cM. Cellular Component: cytoplasm; external side of plasma membrane; extracellular space; focal adhesion; Golgi apparatus; membrane; plasma membrane. Molecular Function: glycoprotein binding; identical protein binding; protein binding. Biological Process: antibacterial humoral response; antigen processing and presentation of endogenous peptide antigen via MHC class I; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; cellular defense response; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; ferric iron import; innate immune response; iron ion homeostasis; iron ion transport; positive regulation of protein binding; positive regulation of receptor-mediated endocytosis; positive regulation of T cell cytokine production; positive regulation of T cell mediated cytotoxicity; protein refolding; regulation of erythrocyte differentiation; response to molecule of bacterial origin; T cell differentiation in the thymus