catalog number :
MBS2544435
products full name :
Rabbit anti Mouse CD5L Monoclonal Antibody
products short name :
[CD5L ]
products name syn :
[ER RECEPTOR CYSTEINE-RICH FAMILY ,SP ALPHA ,SP-alpha]
other names :
[CD5 antigen-like isoform 2; CD5 antigen-like; CD5 antigen-like; CD5 molecule like; Apoptosis inhibitor expressed by macrophages]
products gene name :
[CD5L ]
other gene names :
[CD5L; CD5L; AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA; API6; hAIM]
uniprot entry name :
CD5L_HUMAN
purity :
Affinity purification
storage stability :
Store at -20°C, Avoid freeze / thaw cycles
tested application :
ELISA (EIA)
app notes :
ELISA 1:5000-1:10000
other info1 :
Immunogen: Recombinant Mouse CD5L protein. Buffer: 0.2 um filtered solution in PBS with 5% trehalose
products description :
CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.
ncbi gb acc num :
NM_001347698.1
uniprot summary :
CD5L: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis. Protein type: Receptor, misc.; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q23.1. Cellular Component: extracellular space. Biological Process: cellular defense response