product summary
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company name :
MyBioSource
product type :
antibody
product name :
IL3RA Polyclonal Antibody
catalog :
MBS2542745
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded Human thyroid cancer using IL3RA Polyclonal Antibody at dilution of 1/35
image 2 :
Western Blot analysis of RAW264.7 cells using IL3RA Polyclonal Antibody at dilution of 1/200
product information
catalog number :
MBS2542745
products type :
Antibody
products full name :
IL3RA Polyclonal Antibody
products short name :
[IL3RA]
products name syn :
[IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra]
other names :
[interleukin-3 receptor subunit alpha isoform 2; Interleukin-3 receptor subunit alpha; interleukin-3 receptor subunit alpha; interleukin 3 receptor subunit alpha; CD_antigen: CD123]
products gene name :
[IL3RA]
other gene names :
[IL3RA; IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra; IL3R; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA]
uniprot entry name :
IL3RA_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
300
purity :
Affinity purification
form :
PBS with 0.05% sodium azide, 50% glycerol, PH7.3
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: Synthetic peptide of human IL3RA
other info2 :
Note: Centrifuge before opening to ensure complete recovery of vial contents.
products description :
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GMCSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3.
ncbi gi num :
391224440
ncbi acc num :
NP_002174
ncbi gb acc num :
NM_001267713.1
uniprot acc num :
P26951
ncbi mol weight :
Calculated MW: 43 kDa
ncbi pathways :
ARMS-mediated Activation Pathway (1269471); Apoptosis Pathway (83060); Apoptosis Pathway (470); Axon Guidance Pathway (1270303); Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); DAP12 Interactions Pathway (1269283); DAP12 Signaling Pathway (1269284); Developmental Biology Pathway (1270302)
ncbi summary :
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
uniprot summary :
IL3RA: This is a receptor for interleukin-3. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: Xp22.3 or Yp11.3. Cellular Component: plasma membrane. Molecular Function: interleukin-3 receptor activity; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity. Biological Process: MAPKKK cascade
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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