product summary
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company name :
MyBioSource
product type :
antibody
product name :
PDE5A Polyclonal Antibody
catalog :
MBS2541455
quantity :
0.06 mL
price :
150 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2541455 image 1
Western blot analysis of extracts of various cell lines, using PDE5A antibody.
product information
catalog number :
MBS2541455
products type :
Antibody
products full name :
PDE5A Polyclonal Antibody
products short name :
[PDE5A]
products name syn :
[CN5A; PDE5; CGB-PDE]
other names :
[phosphodiesterase 5A; cGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-specific 3',5'-cyclic phosphodiesterase; phosphodiesterase 5A; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDE]
products gene name :
[PDE5A]
other gene names :
[PDE5A; PDE5A; CN5A; PDE5; CGB-PDE; PDE5; CGB-PDE]
uniprot entry name :
PDE5A_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
875
purity :
Antigen Affinity Purification
storage stability :
Store at -20 degree C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant protein of human PDE5A. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32884
ncbi gi num :
365776143
ncbi mol weight :
Calculated: 94kDa/99kDa; Observed: 100kDa
ncbi pathways :
Hemostasis Pathway (1269340); Nitric Oxide Stimulates Guanylate Cyclase Pathway (1269343); Platelet Homeostasis Pathway (1269341); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); CGMP Effects Pathway (1269344); CGMP-PKG Signaling Pathway (983748); CGMP-PKG Signaling Pathway (985584)
ncbi summary :
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
PDE5A: a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Phosphorylation is regulated by binding of cGMP to the two allosteric sites. Sildenafil (Viagra) is a highly selective and potent inhibitor of PDE5A. Alternative splicing results in four transcript variants encoding distinct isoforms. Protein type: EC 3.1.4.35; Nucleotide Metabolism - purine; Phosphodiesterase. Chromosomal Location of Human Ortholog: 4q27. Cellular Component: cytosol. Molecular Function: 3',5'-cyclic-GMP phosphodiesterase activity; cGMP binding. Biological Process: cGMP catabolic process
size1 :
0.06 mL
price1 :
150 USD
size2 :
0.12 mL
price2 :
225
size3 :
0.2 mL
price3 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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