product summary
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company name :
MyBioSource
product type :
antibody
product name :
GLP1R Polyclonal Antibody
catalog :
MBS2541261
quantity :
0.06 mL
price :
150 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of extracts of various cells, using GLP1R antibody.
product information
catalog number :
MBS2541261
products type :
Antibody
products full name :
GLP1R Polyclonal Antibody
products short name :
[GLP1R]
products name syn :
[GLP-1;GLP-1-R;GLP-1R]
other names :
[glucagon-like peptide 1 receptor; Glucagon-like peptide 1 receptor; glucagon-like peptide 1 receptor; glucagon-like peptide 1 receptor]
products gene name :
[GLP1R]
other gene names :
[Glp1r; Glp1r; GLP-1R; GLP1Rc; GLP-1 receptor; GLP-1-R; GLP-1R]
uniprot entry name :
GLP1R_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse, Rat
sequence length :
463
purity :
Affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant protein of human GLP1R. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34637 / sc-66911. Note: Centrifuge before opening to ensure complete recovery of vial contents.
products description :
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucoseinduced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
ncbi gi num :
111378379
ncbi gb acc num :
NM_021332.2
uniprot acc num :
P43220
ncbi mol weight :
Calculated MW: 53kDa. Observed MW: 53kDa
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway (1367080); G Alpha (s) Signalling Events Pathway (1367085); GPCR Downstream Signaling Pathway (1367084); GPCR Ligand Binding Pathway (1367054); GPCRs, Class B Secretin-like Pathway (198364); Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway (1367762); Glucagon-type Ligand Receptors Pathway (1367082); Insulin Secretion Pathway (777543); Integration Of Energy Metabolism Pathway (1367756); Metabolism Pathway (1367614)
uniprot summary :
GLP1R: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family. Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR. Cellular Component: integral to plasma membrane. Molecular Function: peptide hormone binding; peptide receptor activity; peptide receptor activity, G-protein coupled; receptor activity. Biological Process: associative learning; cAMP-mediated signaling; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, adenylate cyclase activating pathway; hormone secretion; insulin secretion; learning and/or memory; memory; negative regulation of apoptosis; negative regulation of neuron apoptosis; neuropeptide signaling pathway; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of heart contraction; positive regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; regulation of calcium ion transport; regulation of heart contraction; release of sequestered calcium ion into cytosol; response to glucose stimulus; response to stress
size1 :
0.06 mL
price1 :
150 USD
size2 :
0.12 mL
price2 :
225
size3 :
0.2 mL
price3 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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