catalog number : 
MBS2540856
products full name : 
SAFB2 Polyclonal Antibody
products short name : 
[SAFB2]
products name syn : 
[HAP; HET; hsp27 ere tata binding; KIAA0138; SAF B; SAF B2; SAF-B2; SAFB; SAFB1; SAFB2; SAFB2_HUMAN; Scaffold attachment factor B2]
other names : 
[scaffold attachment factor B2; Scaffold attachment factor B2; scaffold attachment factor B2; scaffold attachment factor B2]
products gene name : 
[SAFB2]
other gene names : 
[SAFB2; SAFB2; KIAA0138; SAF-B2]
uniprot entry name : 
SAFB2_HUMAN
reactivity : 
Human, Mouse, Rat
purity : 
Affinity purification
storage stability : 
Store at -20°C. Avoid freeze/thaw cycles.
tested application : 
Western Blot (WB), Immunohistochemistry (IHC)
app notes : 
WB	 1:1000 - 1:2000. IHC: 	1:50 - 1:200
image1 heading : 
Western Blot (WB)
image2 heading : 
Immunohistochemistry (IHC)
other info1 : 
Immunogen: Recombinant protein of human SAFB2. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
other info2 : 
Calculated MW: 12 kDa/107 kDa. Observed MW:  160kDa
products description : 
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes.
ncbi gb acc num : 
NM_014649.2
ncbi mol weight : 
Calculated MW: 12kDa/107kDa. Observed MW: 160kDa
ncbi summary : 
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016]
uniprot summary : 
SAFB2: Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.  Protein type: Nuclear receptor co-regulator; RNA-binding.  Chromosomal Location of Human Ortholog: 19p13.3.  Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus.  Molecular Function: double-stranded DNA binding; identical protein binding; protein binding; sequence-specific DNA binding.  Biological Process: regulation of mRNA processing; regulation of transcription from RNA polymerase II promoter