catalog number :
MBS2540856
products full name :
SAFB2 Polyclonal Antibody
products short name :
[SAFB2]
products name syn :
[HAP; HET; hsp27 ere tata binding; KIAA0138; SAF B; SAF B2; SAF-B2; SAFB; SAFB1; SAFB2; SAFB2_HUMAN; Scaffold attachment factor B2]
other names :
[scaffold attachment factor B2; Scaffold attachment factor B2; scaffold attachment factor B2; scaffold attachment factor B2]
products gene name :
[SAFB2]
other gene names :
[SAFB2; SAFB2; KIAA0138; SAF-B2]
uniprot entry name :
SAFB2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB 1:1000 - 1:2000. IHC: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant protein of human SAFB2. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
other info2 :
Calculated MW: 12 kDa/107 kDa. Observed MW: 160kDa
products description :
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes.
ncbi gb acc num :
NM_014649.2
ncbi mol weight :
Calculated MW: 12kDa/107kDa. Observed MW: 160kDa
ncbi summary :
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016]
uniprot summary :
SAFB2: Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. Protein type: Nuclear receptor co-regulator; RNA-binding. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus. Molecular Function: double-stranded DNA binding; identical protein binding; protein binding; sequence-specific DNA binding. Biological Process: regulation of mRNA processing; regulation of transcription from RNA polymerase II promoter