This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
other
product name :
Choline acetyltransferase assay kit (Ultraviolet method, serum)
catalog :
MBS2540504
quantity :
40 Assays
price :
290 USD
product information
catalog number :
MBS2540504
products type :
Assay Kit
products full name :
Choline acetyltransferase assay kit (Ultraviolet method, serum)
products short name :
[Choline acetyltransferase]
other names :
[choline acetyltransferase, partial; Choline O-acetyltransferase; choline O-acetyltransferase; choline O-acetyltransferase]
other gene names :
[CHAT; CHAT; CMS6; CMS1A; CMS1A2; CHOACTASE; CHOACTase; ChAT; Choline acetylase]
uniprot entry name :
CLAT_HUMAN
sequence length :
95
storage stability :
This product has an approximately 2-2.5 month shelf life upon receipt. Please refer to the expiration date on the kit box.
other info1 :
Samples: Animal Tissue, Serum (Plasma), Whole Blood And Cultured Cells, And Cell Culture Supernatant
products description :
Principle of the Assay: Acetylcholinesterase hydrolysis acetylcholine (Ach) to produce choline and acetic acid. Then cholinereacts with sulfydryl substrate to form TNB (Sym-Trinitrobenzene), a yellow compound which can be measured at412 nm. The concentration of TNB isproportional to the A-CHE activity present.
ncbi gi num :
553229
ncbi mol weight :
70,394 Da
ncbi pathways :
Acetylcholine Neurotransmitter Release Cycle Pathway (1268773); Acetylcholine Synthesis Pathway (198820); Biogenic Amine Synthesis Pathway (198793); Cholinergic Synapse Pathway (217716); Glycerophospholipid Biosynthesis Pathway (1270054); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Neuronal System Pathway (1268763)
ncbi summary :
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
uniprot summary :
CHAT: an enzyme that catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Four alternative splice variants have been described. Protein type: Acetyltransferase; EC 2.3.1.6; Lipid Metabolism - glycerophospholipid. Chromosomal Location of Human Ortholog: 10q11.2. Cellular Component: cytoplasm; cytosol; nucleus. Molecular Function: choline O-acetyltransferase activity. Biological Process: neurotransmitter secretion; phosphatidylcholine biosynthetic process. Disease: Myasthenic Syndrome, Congenital, Associated With Episodic Apnea
size1 :
40 Assays
price1 :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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