Human OPRM1 (Mu-type opioid receptor) ELISA Kit | MyBioSource MBS2540322 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human OPRM1 (Mu-type opioid receptor) ELISA Kit

catalog :

MBS2540322

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2540322

products type :

ELISA Kit

products full name :

Human OPRM1 (Mu-type opioid receptor) ELISA Kit

products short name :

[OPRM1 (Mu-type opioid receptor)]

other names :

[mu-type opioid receptor isoform 1B2; Mu-type opioid receptor; mu-type opioid receptor; opioid receptor, mu 1; Opioid receptor B]

products gene name :

[OPRM1]

other gene names :

[Oprm1; Oprm1; MORA; Oprm; Oprrm1; Ror-b; M-OR-1; MOR-1]

uniprot entry name :

OPRM_RAT

reactivity :

Human

sequence length :

393

specificity :

This kit recognizes natural and recombinantHumanOPRM1. No significant cross-reactivity or interference between HumanOPRM1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 78.125-5000pg/mL. Sensitivity: Min: 46.875pg/mL; Max: 5000pg/mL

products description :

Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanOPRM1concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to OPRM1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for OPRM1and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain OPRM1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of OPRM1.You can calculate the concentration of OPRM1in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

145553980

ncbi acc num :

NP_001033688.2

ncbi gb acc num :

NM_001038599.2

ncbi mol weight :

43,317 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (1376996); Estrogen Signaling Pathway (799190); Estrogen Signaling Pathway (799197); G Alpha (i) Signalling Events Pathway (1377027); G-protein Activation Pathway (1377035); GPCR Downstream Signaling Pathway (1377025); GPCR Ligand Binding Pathway (1376995); GPCRs, Class A Rhodopsin-like Pathway (198500); Morphine Addiction Pathway (552694); Morphine Addiction Pathway (554808)

ncbi summary :

receptor that binds morphine with high affinity [RGD, Feb 2006]

uniprot summary :

MOR-1: a Gi-protein-coupled receptor for beta-endorphin, morphine and other opiates. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Ligand-binding inactivates adenylyl cyclase, and activates a variety of G-beta-gamma-dependent pathways including the MAPK and the PI3K/Akt cascades. Two splice-variant isoforms have been described. Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass. Cellular Component: cytoplasm; dendrite; dendrite cytoplasm; focal adhesion; integral to plasma membrane; lipid raft; membrane; perikaryon; sarcolemma. Molecular Function: beta-endorphin receptor activity; filamin binding; G-protein alpha-subunit binding; G-protein beta-subunit binding; G-protein coupled receptor activity; neuropeptide binding; opioid receptor activity; protein binding; protein C-terminus binding; protein domain specific binding; voltage-gated calcium channel activity. Biological Process: acute inflammatory response to antigenic stimulus; behavioral response to ethanol; dopamine receptor, adenylate cyclase activating pathway; eating behavior; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; locomotory behavior; negative regulation of adenylate cyclase activity; negative regulation of cAMP biosynthetic process; negative regulation of nitric oxide biosynthetic process; opioid receptor, adenylate cyclase inhibiting pathway; positive regulation of appetite; positive regulation of neurogenesis; positive regulation of nitric oxide biosynthetic process; reduction of cytosolic calcium ion concentration; regulation of excitatory postsynaptic membrane potential; regulation of sensory perception of pain; response to cocaine; response to ethanol; response to food; response to lipopolysaccharide; response to morphine; response to radiation; sensory perception of pain; wound healing

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590