catalog number :
MBS2537992
products full name :
IFN-gamma Polyclonal Antibody
products short name :
[IFN-gamma]
products name syn :
[IFNG; Interferon gamma; IFN-gamma; Immune interferon]
other names :
[interferon gamma; Interferon gamma; interferon gamma]
products gene name :
[IFN-gamma]
other gene names :
[IFNG; IFNG; IFI; IFN-g; IFNgamma; TCRalpha; IFN-gamma; IFN-gamma]
uniprot entry name :
IFNG_MUSPF
purity :
Affinity purification.
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
WB, IHC-p, ELISA
app notes :
WB: 1:500-1:2000. IHC: 1:100-1:300. ELISA: 1:4000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Synthesized peptide derived from the Internal region of human IFN-gamma. Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4
other info2 :
Calculated MW: 19 kDa. Observed MW: 17 kDa
products categories :
Cancer; Stem cells
products description :
Interferon gamma (IFNG) is a soluble cytokine that is the only member ofthe type II class of interferons. It is secreted by Th1 cells, cytotoxic Tcells and NK cells. The cytokine is associated with antiviral,immunoregulatory and anti-tumor properties and is a potent activator ofmacrophages. It plays crucial roles in pathogen clearance. Aberrant IFNGexpression is associated with a number of autoinflammatory andautoimmune diseases. It has been identified in many studies as abiomarker for pleural tuberculosis (TB). Mutations in this gene areassociated with aplastic anemia.
ncbi acc num :
NP_001297101.2
ncbi gb acc num :
NM_001310172.2
uniprot summary :
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons ().