product summary
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company name :
MyBioSource
product type :
antibody
product name :
Phospho-Cot (T290) Polyclonal Antibody
catalog :
MBS2535471
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2535471 image 1
Western Blot analysis of various cells with Phospho-Cot (Thr290) Polyclonal Antibody
product information
catalog number :
MBS2535471
products type :
Antibody
products full name :
Phospho-Cot (T290) Polyclonal Antibody
products short name :
[Cot]
products name syn :
[MAP3K8; COT; ESTF; Mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2; TPL-2]
products gene name :
[Cot]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF), ELISA (EIA)
app notes :
WB 1:500-1:2000. IHC 1:100-1:300. IF 1:200-1:1000. ELISA 1:4000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Synthesized peptide derived from human Cot around the phosphorylation site of T290. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Calculated MW: 53 kDa. Observed MW: 60 kDa. Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4
products categories :
Phospho Antibodies
products description :
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8) is a Protein Coding gene. Diseases associated with MAP3K8 include Lung Cancer. Among its related pathways are IL-1 signaling pathway and 4-1BB Pathway. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAP3K5.
uniprot acc num :
P41279
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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