antibody

Phospho-Cdk5 (Y15) Polyclonal Antibody

MBS2534755

0.02 mL

110 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry, enzyme immunoassay

Antibody

Phospho-Cdk5 (Y15) Polyclonal Antibody

[Cdk5]

[CDK5,CDKN5,Cyclin-dependent kinase 5,Cell division protein kinase 5,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit]

[CDK5; CDK5 protein; cyclin-dependent-like kinase 5; cyclin-dependent kinase 5; CDK5 protein]

[Cdk5]

[CDK5; CDK5; LIS7; PSSALRE]

Q6IAW3_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat, Monkey

292

Affinity purification

PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB), Immunohistochemistry (IHC)-p, ELISA (EIA)

WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Western Blot (WB)

Immunogen: Synthesized peptide derived from human Cdk5 around the phosphorylation site of Tyr15

Phospho Antibodies

Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyc

48146199

CAG33322.1

Q00535

Calculated MW: 33kDa. Observed MW: 33kDa

Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (1270303); BDNF Signaling Pathway (712093); CRMPs In Sema3A Signaling Pathway (1270310); Cocaine Addiction Pathway (546258); Cocaine Addiction Pathway (546273)

This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

0.02 mL

110 USD

0.06 mL

150

0.12 mL

225

0.2 mL

360