Monkey OC/BGP (Osteocalcin) ELISA Kit | MyBioSource MBS2533624 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Monkey OC/BGP (Osteocalcin) ELISA Kit

catalog :

MBS2533624

quantity :

24-Strip-Wells

price :

210 USD

product information

catalog number :

MBS2533624

products type :

ELISA Kit

products full name :

Monkey OC/BGP (Osteocalcin) ELISA Kit

products short name :

[Osteocalcin]

other names :

[osteocalcin preproprotein; Osteocalcin; osteocalcin; bone gamma-carboxyglutamate protein; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein]

products gene name :

[OC/BGP]

other gene names :

[BGLAP; BGLAP; OC; BGP; OCN; BGP]

uniprot entry name :

OSTCN_HUMAN

reactivity :

Monkey

sequence length :

100

specificity :

This kit recognizes natural and some recombinant Monkey OC/BGP. No significant cross-reactivity or interference between Monkey OC/BGP and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.781-50ng/mL . Sensitivity: Min: 0.469ng/mL ; Max: 50ng/mL

products description :

Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Monkey OC/BGP concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Monkey OC/BGP. Standards or samples are added to appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibodies specific for Monkey OC/BGP and Avidin-Horseradish Peroxidase (HRP) conjugate are added to each micro plate well successively and incubated. After incubation, free components are washed away. Then the Substrate Reagent is added to each well, only those wells that contain Monkey OC/BGP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction will be terminated by adding Stop Solution and appears yellow in color. The optical density (OD) can be measured with spectrophotometry at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Monkey OC/BGP. The concentration of Monkey OC/BGP in samples can be calculated by comparing the OD of the samples with the standard curve.

ncbi gi num :

40316933

ncbi acc num :

NP_954642.1

ncbi gb acc num :

NM_199173.5

ncbi mol weight :

10,963 Da

ncbi pathways :

FGF Signaling Pathway (137989); Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway (1268702); Gamma-carboxylation Of Protein Precursors Pathway (1268704); Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway (1268703); Glucocorticoid Receptor Regulatory Network Pathway (138014); Interleukin-11 Signaling Pathway (698753); Metabolism Of Proteins Pathway (1268677); Notch-mediated HES/HEY Network Pathway (169347); Post-translational Protein Modification Pathway (1268701); Regulation Of Retinoblastoma Protein Pathway (137916)

ncbi summary :

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]

uniprot summary :

osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. Protein type: Cell development/differentiation; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q22. Cellular Component: cytoplasm; dendrite; endoplasmic reticulum lumen; extracellular space; Golgi lumen; perikaryon; rough endoplasmic reticulum. Molecular Function: calcium ion binding; hydroxyapatite binding; structural constituent of bone; structural molecule activity. Biological Process: bone mineralization; cell adhesion; cell aging; cellular protein metabolic process; ER to Golgi vesicle-mediated transport; odontogenesis; osteoblast development; osteoblast differentiation; peptidyl-glutamic acid carboxylation; post-translational protein modification; regulation of bone mineralization; regulation of bone resorption; regulation of osteoclast differentiation; response to activity; response to drug; response to estrogen stimulus; response to ethanol; response to glucocorticoid stimulus; response to gravity; response to hydroxyisoflavone; response to mechanical stimulus; response to testosterone stimulus; response to vitamin D; response to vitamin K; response to zinc ion; signal peptide processing; skeletal development

size1 :

24-Strip-Wells

price1 :

210 USD

size2 :

48-Strip-Wells

price2 :

400

size3 :

96-Strip-Wells

price3 :

475

size4 :

5x96-Strip-Wells

price4 :

1975

size5 :

10x96-Strip-Wells

price5 :

3480