Mouse CNR1 (Cannabinoid Receptor 1, Brain) ELISA Kit | MyBioSource MBS2533482 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse CNR1 (Cannabinoid Receptor 1, Brain) ELISA Kit

catalog :

MBS2533482

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2533482

products type :

ELISA Kit

products full name :

Mouse CNR1 (Cannabinoid Receptor 1, Brain) ELISA Kit

products short name :

[Cannabinoid Receptor 1, Brain]

other names :

[cannabinoid receptor 1; Cannabinoid receptor 1; cannabinoid receptor 1; cannabinoid receptor 1; Brain-type cannabinoid receptor]

products gene name :

[CNR1]

other gene names :

[Cnr1; Cnr1; SKR6R; Skr6; CB-R; CB1]

uniprot entry name :

CNR1_RAT

reactivity :

Mouse

sequence length :

473

specificity :

This kit recognizes natural and recombinant Mouse CNR1. No significant cross-reactivity or interference between Mouse CNR1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Biological Fluids. Assay Type: Sandwich. Detection Range: 0.313-20ng/mL . Sensitivity: Min: 0.188ng/mL ; Max: 20ng/mL

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Mouse CNR1 concentrations in serum, plasma and other biological fluids. Principle of the Assay This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to CNR1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for CNR1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain CNR1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of CNR1. You can calculate the concentration of CNR1 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

6978673

ncbi acc num :

NP_036916.1

ncbi gb acc num :

NM_012784.4

uniprot acc num :

P20272

ncbi mol weight :

52,845 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (1333935); G Alpha (i) Signalling Events Pathway (1333966); GPCR Downstream Signaling Pathway (1333964); GPCR Ligand Binding Pathway (1333934); GPCRs, Class A Rhodopsin-like Pathway (198500); GPCRs, Other Pathway (198454); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462); Rap1 Signaling Pathway (869320); Rap1 Signaling Pathway (878042)

ncbi summary :

G-protein coupled receptor for psychoactive cannabinoids; may mediate inhibition of NO production and participate in retrograde signaling by endocannabinoids [RGD, Feb 2006]

uniprot summary :

CNR1: Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1. Cellular Component: axon; growth cone; integral to membrane; intracellular membrane-bound organelle; lipid raft; plasma membrane. Molecular Function: cannabinoid receptor activity; drug binding; protein binding. Biological Process: aging; axonal fasciculation; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; glucose homeostasis; learning and/or memory; maternal process involved in pregnancy; memory; negative regulation of action potential; negative regulation of blood pressure; negative regulation of dopamine secretion; negative regulation of fatty acid beta-oxidation; negative regulation of ion transport; negative regulation of mast cell activation; negative regulation of nitric-oxide synthase activity; positive regulation of acute inflammatory response to antigenic stimulus; positive regulation of apoptosis; positive regulation of blood pressure; positive regulation of fever; regulation of insulin secretion; regulation of lipid metabolic process; regulation of synaptic transmission, GABAergic; regulation of synaptic transmission, glutamatergic; response to cocaine; response to ethanol; response to lipopolysaccharide; response to morphine; response to nicotine; response to nutrient; sensory perception of pain; spermatogenesis

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590