ICAM-3 (Intercellular Adhesion Molecule 3) ELISA Kit | MyBioSource MBS2533396 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

ICAM-3 (Intercellular Adhesion Molecule 3) ELISA Kit

catalog :

MBS2533396

quantity :

24-Strip-Wells

price :

215 USD

product information

catalog number :

MBS2533396

products type :

ELISA Kit

products full name :

ICAM-3 (Intercellular Adhesion Molecule 3) ELISA Kit

products short name :

[Intercellular Adhesion Molecule 3]

other names :

[intercellular adhesion molecule 3 isoform 1; Intercellular adhesion molecule 3; intercellular adhesion molecule 3; intercellular adhesion molecule 3; CDw50; ICAM-R; CD_antigen: CD50]

products gene name :

[ICAM-3]

other gene names :

[ICAM3; ICAM3; CD50; CDW50; ICAM-R; ICAM-3]

uniprot entry name :

ICAM3_HUMAN

sequence length :

547

specificity :

This kit recognizes Human HTRA1 in samples. No significant cross-reactivity or interference between Human HTRA1 and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 0.31-20ng/mL. Sensitivity: 0.19ng/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human HTRA1 were tested 20 times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human HTRA1 were tested on 3 different plates, 20 replicates in each plate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human HTRA1 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human HTRA1. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human HTRA1 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human HTRA1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human HTRA1. You can calculate the concentration of Human HTRA1 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

167466207

ncbi acc num :

NP_002153.2

ncbi gb acc num :

NM_002162.4

ncbi mol weight :

59,541 Da

ncbi pathways :

Adaptive Immune System Pathway (1269171); C-type Lectin Receptors (CLRs) Pathway (1269303); CD209 (DC-SIGN) Signaling Pathway (1269309); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Extracellular Matrix Organization Pathway (1270244); IL-5 Signaling Pathway (198770); Immune System Pathway (1269170); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (1269201); Innate Immune System Pathway (1269203)

ncbi summary :

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

uniprot summary :

ICAM3: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. Belongs to the immunoglobulin superfamily. ICAM family. Protein type: Membrane protein, integral; Immunoglobulin superfamily; Cell adhesion. Chromosomal Location of Human Ortholog: 19p13.3-p13.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: integrin binding; protein binding; receptor binding. Biological Process: cell adhesion; cell-cell adhesion; extracellular matrix organization and biogenesis; innate immune response; regulation of immune response; stimulatory C-type lectin receptor signaling pathway

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590