Human ADAMTS7 (A Disintegrin And Metalloproteinase With Thrombospondin 7) ELISA Kit | MyBioSource MBS2533367 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human ADAMTS7 (A Disintegrin And Metalloproteinase With Thrombospondin 7) ELISA Kit

catalog :

MBS2533367

quantity :

24-Strip-Wells

price :

215 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS2533367

products type :

ELISA Kit

products full name :

Human ADAMTS7 (A Disintegrin And Metalloproteinase With Thrombospondin 7) ELISA Kit

products short name :

[A Disintegrin And Metalloproteinase With Thrombospondin 7]

other names :

[A disintegrin and metalloproteinase with thrombospondin motifs 7 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 7; A disintegrin and metalloproteinase with thrombospondin motifs 7; ADAM metallopeptidase with thrombospondin type 1 motif 7; COMPase]

products gene name :

[ADAMTS7]

other gene names :

[ADAMTS7; ADAMTS7; ADAM-TS7; ADAMTS-7; ADAM-TS 7; ADAM-TS 7; ADAM-TS7; ADAMTS-7]

uniprot entry name :

ATS7_HUMAN

reactivity :

Human

sequence length :

1686

specificity :

This kit recognizes Human ADAMTS4 in samples. No significant cross-reactivity or interference between HumanADAMTS4and analogues was observed.

storage stability :

Store at 4 degree C.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Other Biological Fluids. Assay Type: Quantitative Sandwich. Detection Range: 62.5-4000pg/mL. Sensitivity: 37.5pg/mL.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, midrange and high level HumanADAMTS4were tested 20times on one plate, respectively. Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, midrange and high level HumanADAMTS4were testedon 3 different plates, 20 replicates in eachplate.

products description :

Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human ADAMTS4 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human ADAMTS4. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human ADAMTS4 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human ADAMTS4, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human ADAMTS4. You can calculate the concentration of Human ADAMTS4 in the samples by comparing the OD of the samples to the standard curve.

ncbi gi num :

38683827

ncbi acc num :

NP_055087.2

ncbi gb acc num :

NM_014272.4

ncbi mol weight :

184,095 Da

ncbi pathways :

Metabolism Of Proteins Pathway (1268677); O-glycosylation Of TSR Domain-containing Proteins Pathway (1268735); O-linked Glycosylation Pathway (1268734); Post-translational Protein Modification Pathway (1268701)

ncbi summary :

The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016]

uniprot summary :

ADAMTS7: Metalloprotease that may play a role in the degradation of COMP. Protein type: Protease; Cell surface; Motility/polarity/chemotaxis; EC 3.4.24.-; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 15q24.2. Cellular Component: cell surface; endoplasmic reticulum lumen; proteinaceous extracellular matrix. Molecular Function: metalloendopeptidase activity; metallopeptidase activity; protein binding; zinc ion binding. Biological Process: cellular protein metabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification; protein amino acid O-linked glycosylation; proteolysis involved in cellular protein catabolic process

size1 :

24-Strip-Wells

price1 :

215 USD

size2 :

48-Strip-Wells

price2 :

410

size3 :

96-Strip-Wells

price3 :

490

size4 :

5x96-Strip-Wells

price4 :

2040

size5 :

10x96-Strip-Wells

price5 :

3590

more info or order :

MyBioSource product webpage