catalog number :
MBS2532912
products full name :
Human CASP4 (Caspase 4) CLIA Kit
products short name :
[CASP4 (Caspase 4)]
other names :
[caspase 4; caspase 4; caspase 4, apoptosis-related cysteine peptidase]
products gene name :
[CASP4]
other gene names :
[Casp4; Casp11]
specificity :
This kit recognizes natural and recombinant CASP4. No significant cross-reactivity or interference between CASP4 and analogues was observed.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Assay Type: Sandwich. Detection Range: 31.25-2000pg/mL. Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL
products description :
Intended Uses: This CLIA kit applies to the in vitro quantitative determination of CASP4 concentrations in serum, plasma and other biological fluids. Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to CASP4. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for CASP4 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain CASP4, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of CASP4. You can calculate the concentration of CASP4 in the samples by comparing the RLU value of the samples to the standard curve.
ncbi acc num :
NP_446188.2
ncbi gb acc num :
NM_053736.2
ncbi pathways :
Apoptosis Pathway (219785)
ncbi summary :
cysteine-aspartic acid protease (caspase); involved with the terminal stage of apoptosis; may also be involved with response to inflammation [RGD, Feb 2006]
size4 :
10x96-Strip-Wells