catalog number :
MBS253272
products type :
Recombinant Protein
products full name :
Alpha-Fetoprotein (aFP)
products short name :
Alpha-Fetoprotein (aFP)
other names :
alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-fetoglobulin; alpha-1-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
other gene names :
AFP; AFP; AFPD; FETA; HPAFP; HPAFP
uniprot entry name :
FETA_HUMAN
sequence :
KH IEESQALSKQ SCALYQTLGD YKLQNLFLIG YTRKAPQLTS AELlDLTGKM VSIASTCCQL SEEKWSGCGE GMADIFIGHL CIRNEASPVN SGISHCCNSS YSNRRLCITS FLRDETYAPP PFSEDKFIFH KDLCQAQGKA LQTMKQHLI NLVKQKPELT EEQLAAVTAD FSGLLEKCCK AQDQEVCFTE EGPKLlSKTR DALGV
form :
Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
storage stability :
Store at 2-8 degree C for one months; for long term storage, store at -20 degree C or -80 degree C.
other info1 :
Tag Information: two N-terminal Tags, His-tag and S-tag. Endotoxin Level: <1.0EU per 1ug (determined by the LAL method).
other info2 :
Organism: Mus musculus (Mouse). Usage: Reconstitute in sterile PBS, pH7.4.
ncbi acc num :
NP_001125.1
ncbi gb acc num :
NM_001134.2
ncbi mol weight :
28.7kDa
ncbi pathways :
Direct P53 Effectors Pathway 137939!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Hippo Signaling Pathway 749777!!Hippo Signaling Pathway 750388
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]