product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD109 Polyclonal Antibody
catalog :
MBS2530288
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD109 Polyclonal Antibody at dilution 1:30
image 2 :
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CD109 Polyclonal Antibody at dilution 1:30
product information
catalog number :
MBS2530288
products type :
Antibody
products full name :
CD109 Polyclonal Antibody
products short name :
[CD109]
products name syn :
[CPAMD7; RP11-525G3.1]
other names :
[CD109 antigen isoform 3 preproprotein; CD109 antigen; CD109 antigen; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Gov platelet alloantigens; activated T-cell marker CD109; platelet-specific Gov antigen; CD109 molecule; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Platelet-specific Gov antigen; p180; r150; CD_antigen: CD109]
products gene name :
[CD109]
other gene names :
[CD109; CD109; p180; r150; CPAMD7; CPAMD7]
uniprot entry name :
CD109_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
1368
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:25-1:100
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide of human CD109
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products description :
This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
ncbi gi num :
227430303
ncbi acc num :
NP_001153059
ncbi gb acc num :
NM_001159588.2
uniprot acc num :
Q6YHK3
ncbi summary :
This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
uniprot summary :
CD109: Modulates negatively TGFB1 signaling in keratinocytes. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 6q13. Cellular Component: extracellular space; cell surface; plasma membrane. Molecular Function: serine-type endopeptidase inhibitor activity; transforming growth factor beta binding. Biological Process: negative regulation of protein amino acid phosphorylation; hair follicle development; negative regulation of transforming growth factor beta receptor signaling pathway; regulation of keratinocyte differentiation
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
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