product summary
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company name :
MyBioSource
product type :
antibody
product name :
GPR177 Antibody
catalog :
MBS2529770
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
mouse liver tissue were subjected to SDS PAGE followed by western blot with GPRI77 antibody at dilution of 1:400
image 2 :
Immunohistochemical of paraffin-embedded human ovary using GPR177 antibody at dilution of 1 :100 (under lOx lens)
image 3 :
Immunohistochemical of paraffm-embedded human ovary using GPR177 antibody at dilution of 1: 1 00 (under 40x lens)
product information
catalog number :
MBS2529770
products type :
Antibody
products full name :
GPR177 Antibody
products short name :
[GPR177]
products name syn :
[Clorfl39; EV1; FLJ23091; MGC131760; MGC14878; MRP; WLS]
other names :
[GPR177 protein, partial; Protein wntless homolog; protein wntless homolog; G protein-coupled receptor 177; integral membrane protein GPR177; protein evenness interrupted homolog; putative NF-kappa-B-activating protein 373; putative NFkB activating protein 373; wntless Wnt ligand secretion mediator; Integral membrane protein GPR177; Protein evenness interrupted homolog; EVI; Putative NF-kappa-B-activating protein 373]
products gene name :
[GPR177]
other gene names :
[WLS; WLS; EVI; MRP; GPR177; mig-14; C1orf139; C1orf139; GPR177; EVI]
uniprot entry name :
WLS_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
487
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:200-1:2000. IHC: 1:50-1:200
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry
image3 heading :
Immunohistochemistry
other info1 :
Immunogen: Fusion protein of GPR177. Calculated Molecular Weight: 541aa; 62kd. Observed Molecular Weight: 46-62 kDa
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
ncbi gi num :
62913992
ncbi acc num :
AAH07211.2
uniprot acc num :
BC110826
ncbi mol weight :
51,571 Da
ncbi pathways :
Disease Pathway (530764); Signal Transduction Pathway (477114); Signaling By WNT In Cancer Pathway (1127614); Signaling By Wnt Pathway (106510); WNT Ligand Biogenesis And Trafficking Pathway (833832); WNT Ligand Secretion Is Abrogated By The PORCN Inhibitor LGK974 Pathway (1127634)
uniprot summary :
GPR177: Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. Belongs to the wntless family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1p31.3. Cellular Component: Golgi membrane; dendrite cytoplasm; cytoplasmic vesicle membrane; early endosome membrane; integral to membrane; plasma membrane. Molecular Function: Wnt-protein binding; protein binding; signal transducer activity; mu-type opioid receptor binding. Biological Process: Wnt receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; mesoderm formation; anterior/posterior axis specification
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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