catalog number :
MBS2529630
products full name :
NCR1 Polyclonal Antibody
products short name :
[NCR1]
products name syn :
[LY94; CD335; NKP46; NK-p46]
other names :
[Natural cytotoxicity triggering receptor 1; Natural cytotoxicity triggering receptor 1; natural cytotoxicity triggering receptor 1; NK cell-activating receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural killer cell p46-related protein; natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD_antigen: CD335]
products gene name :
[NCR1]
other gene names :
[NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46]
uniprot entry name :
NCTR1_HUMAN
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:50-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide of human NCR1
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products description :
Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. NCR1 has also been designated as CD335 (cluster of differentiation 335). Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Interacts with CD247 and FCER1G. Selectively expressed by both resting and activated NK cells.
ncbi acc num :
NP_001138929
ncbi pathways :
Natural Killer Cell Mediated Cytotoxicity Pathway (83079); Natural Killer Cell Mediated Cytotoxicity Pathway (490)
uniprot summary :
NCR1: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Belongs to the natural cytotoxicity receptor (NCR) family. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis; Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 19q13.42. Cellular Component: SWI/SNF complex; integral to plasma membrane. Molecular Function: receptor signaling protein activity. Biological Process: regulation of natural killer cell mediated cytotoxicity; cellular defense response; natural killer cell activation; signal transduction