product summary
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company name :
MyBioSource
product type :
antibody
product name :
SIGLEC5 Polyclonal Antibody
catalog :
MBS2529443
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS2529443 image 1
Western Blot analysis of Mouse liver tissue using SIGLEC5 Polyclonal Antibody at dilution of 1:350
image 2 :
MyBioSource MBS2529443 image 2
Immunohistochemistry of paraffin-embedded Human gastic cancer using SIGLEC5 Polyclonal Antibody at dilution of 1:30
image 3 :
MyBioSource MBS2529443 image 3
Immunohistochemistry of paraffin-embedded Human colon cancer using SIGLEC5 Polyclonal Antibody at dilution of 1:30
product information
catalog number :
MBS2529443
products type :
Antibody
products full name :
SIGLEC5 Polyclonal Antibody
products short name :
[SIGLEC5]
products name syn :
[CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5]
other names :
[sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin 5; sialic acid-binding Ig-like lectin 5; CD33 antigen-like 2; OB-binding protein 2; obesity-binding protein 2; sialic acid-binding immunoglobulin-like lectin 5; sialic acid binding Ig-like lectin 5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; OB-binding protein 2; CD_antigen: CD170]
products gene name :
[SIGLEC5]
other gene names :
[SIGLEC5; SIGLEC5; CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5; CD33L2; OBBP2; Siglec-5; OB-BP2; OB-binding protein 2]
uniprot entry name :
SIGL5_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
551
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:200-1:1000. IHC: 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
products description :
Background: This gene encodes a member of the sialic acid-binding immunoglobulinlike lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
ncbi gi num :
4502659
ncbi acc num :
NP_003821.1
ncbi gb acc num :
NM_003830.3
uniprot acc num :
BC029896
ncbi summary :
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
uniprot summary :
SIGLEC5: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. Protein type: Cell adhesion; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: integral to membrane. Molecular Function: carbohydrate binding. Biological Process: cell adhesion
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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