product summary
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company name :
MyBioSource
product type :
antibody
product name :
CCL6 Polyclonal Antibody
catalog :
MBS2529419
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2529419
products type :
Antibody
products full name :
CCL6 Polyclonal Antibody
products short name :
CCL6
products name syn :
C10, Scya6, MRP-1
other names :
C-C motif chemokine 6; C-C motif chemokine 6; C-C motif chemokine 6; CC chemokine C10; small inducible cytokine A6; small-inducible cytokine A6; chemokine (C-C motif) ligand 6; Protein C10; Small-inducible cytokine A6Cleaved into the following 2 chains:CCL6(22-95); CCL6(23-95)
products gene name :
CCL6
other gene names :
Ccl6; Ccl6; c10; MRP-1; Scya6; C10; Scya6
uniprot entry name :
CCL6_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
116
purity :
Affinity purification
concentration :
2.8mg/mL
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:25-1:100
products description :
Background/Introduction: In mice, Ccl6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of Ccl6 is greatly reduced.Ccl6 can also be induced in the mouse lung by the cytokine interleukin 13
ncbi gi num :
6677883
ncbi acc num :
NP_033165
ncbi gb acc num :
NM_009139.3
ncbi mol weight :
12,984 Da
ncbi pathways :
Chemokine Signaling Pathway (99271); Chemokine Signaling Pathway (672435); Chemokine Signaling Pathway (96864); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460)
uniprot summary :
CCL6: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis. Cellular Component: extracellular space; extracellular region. Molecular Function: chemokine activity; cytokine activity. Biological Process: immune response; chemotaxis
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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