product summary
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company name :
MyBioSource
product type :
antibody
product name :
PDE6C Polyclonal Antibody
catalog :
MBS2529219
quantity :
0.06 mL
price :
195 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2529219
products type :
Antibody
products full name :
PDE6C Polyclonal Antibody
products short name :
PDE6C
products name syn :
COD4; ACHM5; PDEA2
other names :
PDE6C protein, partial; Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'; cGMP phosphodiesterase 6C; phosphodiesterase 6C, cGMP-specific, cone, alpha prime; cGMP phosphodiesterase 6C
products gene name :
PDE6C
other gene names :
PDE6C; PDE6C; COD4; ACHM5; PDEA2; PDEA2
uniprot entry name :
PDE6C_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
858
purity :
Antigen affinity purification
concentration :
2.8mg/mL
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:500-1:2000
other info1 :
Immunogen: Synthetic peptide of human PDE6C. Calculated Molecular Weight: 99kDa
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products description :
Cone cGMP-specific 3', 5'-cyclic phosphodiesterase subunit alpha' is an enzyme that in humans is encoded by the PDE6C gene. This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).
ncbi gi num :
108752088
ncbi acc num :
AAI11378.1
ncbi mol weight :
99kDa
ncbi pathways :
Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); Visual Signal Transduction: Cones Pathway (137926)
ncbi summary :
This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4). [provided by RefSeq, Mar 2010]
uniprot summary :
PDE6C: Defects in PDE6C are the cause of cone dystrophy type 4 (COD4). An early-onset cone dystrophy. Cone dystrophies are retinal dystrophies characterized by progressive degeneration of the cone photoreceptors with preservation of rod function, as indicated by electroretinogram. However, some rod involvement may be present in some cone dystrophies, particularly at late stage. Affected individuals suffer from photophobia, loss of visual acuity, color vision and central visual field. Another sign is the absence of macular lesions for many years. Cone dystrophies are distinguished from the cone-rod dystrophies in which some loss of peripheral vision also occurs. Belongs to the cyclic nucleotide phosphodiesterase family. Protein type: EC 3.1.4.35; Phosphodiesterase. Chromosomal Location of Human Ortholog: 10q24. Cellular Component: plasma membrane. Molecular Function: 3 ,5 -cyclic-GMP phosphodiesterase activity; metal ion binding; cGMP binding. Biological Process: phototransduction, visible light; retinal cone cell development; visual perception; metabolic process. Disease: Cone Dystrophy 4
size1 :
0.06 mL
price1 :
195 USD
size2 :
0.12 mL
price2 :
270
size3 :
0.2 mL
price3 :
435
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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