CD151 Antibody | MyBioSource MBS2529122 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

CD151 Antibody

catalog :

MBS2529122

quantity :

0.06 mL

price :

150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of extracts of various cell lines, using CD151 antibody.

image 2 :

Immunohistochemistry of paraffin-embedded human stomach using CD151 antibody at dilution of 1:200 (x400 lens)

product information

catalog number :

MBS2529122

products type :

Antibody

products full name :

CD151 Antibody

products short name :

[CD151]

products name syn :

[GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24]

other names :

[CD151 antigen; CD151 antigen; CD151 antigen; CD151 antigen (Raph blood group); hemidesmosomal tetraspanin CD151; membrane glycoprotein SFA-1; platelet surface glycoprotein gp27; platelet-endothelial cell tetraspan antigen 3; platelet-endothelial tetraspan antigen 3; tetraspanin-24; tspan-24; CD151 molecule (Raph blood group); GP27; Membrane glycoprotein SFA-1; Platelet-endothelial tetraspan antigen 3; PETA-3; Tetraspanin-24; Tspan-24; CD_antigen: CD151]

products gene name :

[CD151]

other gene names :

[CD151; CD151; GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24; TSPAN24; PETA-3; Tspan-24]

uniprot entry name :

CD151_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

253

purity :

Antigen affinity purification

concentration :

1mg/mL

storage stability :

Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Recommended Dilution:. WB: 1:500-1:2000. IHC: 1:50-1:200

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info2 :

Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18753-R / sc-33123

products description :

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

ncbi gi num :

21237751

ncbi acc num :

NP_620599.1

ncbi gb acc num :

NM_139030.3

ncbi mol weight :

28kDa

ncbi pathways :

Alpha6-Beta4 Integrin Signaling Pathway (198807); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Collagen Formation Pathway (645288); Extracellular Matrix Organization Pathway (576262); Type I Hemidesmosome Assembly Pathway (160970)

ncbi summary :

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

CD151: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD). NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor. Belongs to the tetraspanin (TM4SF) family. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: focal adhesion; membrane; integral to plasma membrane; plasma membrane; cytosol. Molecular Function: integrin binding; protein binding. Biological Process: T cell proliferation; cell migration; extracellular matrix organization and biogenesis; hemidesmosome assembly; cell adhesion. Disease: Raph Blood Group System; Nephropathy With Pretibial Epidermolysis Bullosa And Deafness

size1 :

0.06 mL

price1 :

150 USD

size2 :

0.12 mL

price2 :

225

size3 :

0.2 mL

price3 :

360

more info or order :

MyBioSource product webpage