product summary
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company name :
MyBioSource
product type :
antibody
product name :
CRTAM Polyclonal Antibody
catalog :
MBS2528978
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CRTAM Polyclonal Antibody at dilution 1:30
product information
catalog number :
MBS2528978
products type :
Antibody
products full name :
CRTAM Polyclonal Antibody
products short name :
[CRTAM]
products name syn :
[CD355]
other names :
[cytotoxic and regulatory T-cell molecule Isoform 2; Cytotoxic and regulatory T-cell molecule; cytotoxic and regulatory T-cell molecule; class I MHC restricted T cell associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; cytotoxic and regulatory T cell molecule; Class-I MHC-restricted T-cell-associated molecule; CD_antigen: CD355]
products gene name :
[CRTAM]
other gene names :
[CRTAM; CRTAM; CD355]
uniprot entry name :
CRTAM_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
194
purity :
Affinity purification
concentration :
0.2mg/mL
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:25-1:100
image1 heading :
Immunohistochemistry (IHC)
products description :
Background/Introduction: The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferongamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
ncbi gi num :
755571554
ncbi acc num :
NP_001291711.1
ncbi gb acc num :
NM_001304782.1
uniprot acc num :
BC070266
ncbi mol weight :
22,256 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413)
ncbi summary :
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]
uniprot summary :
CRTAM: Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Belongs to the nectin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 11q24.1. Cellular Component: integral to membrane; plasma membrane. Molecular Function: receptor binding. Biological Process: regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; detection of tumor cell; activated T cell proliferation; detection of stimulus; cell recognition; positive regulation of natural killer cell mediated cytotoxicity; T cell mediated cytotoxicity; positive regulation of cytokine secretion
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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