catalog number :
MBS2528368
products full name :
LAG3 Antibody
products short name :
[LAG3]
products name syn :
[CD223]
other names :
[lymphocyte activation gene 3 protein; Lymphocyte activation gene 3 protein; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Protein FDC; CD_antigen: CD223]
products gene name :
[LAG3]
other gene names :
[LAG3; LAG3; CD223; FDC; LAG-3]
uniprot entry name :
LAG3_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:200-1:2000
image1 heading :
Testing Data
other info1 :
Immunogen: Fusion protein of LAG3. Calculated Molecular Weight: 525aa-57kDa. Observed Molecular Weight: 54kDa; 60-65kDa
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26368 / sc-33319
ncbi acc num :
NP_002277.4
ncbi gb acc num :
NM_002286.5
ncbi mol weight :
39,103 Da
ncbi summary :
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
uniprot summary :
LAG3: Involved in lymphocyte activation. Binds to HLA class-II antigens. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13.32. Cellular Component: integral to membrane; external side of plasma membrane. Molecular Function: transmembrane receptor activity; antigen binding; MHC class II protein binding. Biological Process: cell surface receptor linked signal transduction; negative regulation of interleukin-2 biosynthetic process; positive regulation of natural killer cell mediated cytotoxicity; negative regulation of T cell activation