S1PR3 Polyclonal Antibody | MyBioSource MBS2528152 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

S1PR3 Polyclonal Antibody

catalog :

MBS2528152

quantity :

0.02 mL

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot analysis of Human fetal brain tissue using S1PR3 Polyclonal Antibody at dilution of 1:700

image 2 :

Immunohistochemistry of paraffin-embedded Human cervical cancer using S1PR3 Polyclonal Antibody at dilution of 1:30

image 3 :

Immunohistochemistry of paraffin-embedded Human thyroid cancer using S1PR3 Polyclonal Antibody at dilution of 1:30

product information

catalog number :

MBS2528152

products type :

Antibody

products full name :

S1PR3 Polyclonal Antibody

products short name :

[S1PR3]

products name syn :

[EDG3; LPB3; S1P3; EDG-3]

other names :

[sphingosine 1-phosphate receptor 3; Sphingosine 1-phosphate receptor 3; sphingosine 1-phosphate receptor 3; G protein-coupled receptor, endothelial differentiation gene-3; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; endothelial differentiation G-protein coupled receptor 3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; sphingosine 1-phosphate receptor Edg-3; sphingosine-1-phosphate receptor 3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3]

products gene name :

[S1PR3]

other gene names :

[S1PR3; S1PR3; EDG3; LPB3; S1P3; EDG-3; EDG3; S1P receptor 3; S1P3; S1P receptor Edg-3]

uniprot entry name :

S1PR3_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse

sequence length :

378

purity :

Affinity purification

storage stability :

Store at -20°C. Avoid freeze/thaw cycles.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB: 1:1000-1:5000. IHC: 1:25-1:100

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Immunogen: Synthetic peptide of human S1PR3. Calculated MW: 42kDa

other info2 :

Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. Cellular localization : Cell membrane

products description :

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.

ncbi gi num :

38788193

ncbi acc num :

NP_005217

ncbi gb acc num :

NM_005226.3

uniprot acc num :

Q99500

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Lysosphingolipid And LPA Receptors Pathway (106376); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462)

ncbi summary :

uniprot summary :

S1PR3: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 9q22.1-q22.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: integrin binding; G-protein coupled receptor activity; lipid binding. Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; anatomical structure morphogenesis; regulation of interleukin-1 beta production; positive regulation of cell proliferation; cytokine production; G-protein signaling, adenylate cyclase inhibiting pathway; inflammatory response

size1 :

0.02 mL

price1 :

110 USD

size2 :

0.06 mL

price2 :

150

size3 :

0.12 mL

price3 :

225

size4 :

0.2 mL

price4 :

360

more info or order :

MyBioSource product webpage