product summary
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company name :
MyBioSource
product type :
antibody
product name :
ADAMTS14 Polyclonal Antibody
catalog :
MBS2527871
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ADAMTS14 Polyclonal Antibody at dilution 1:50
product information
catalog number :
MBS2527871
products type :
Antibody
products full name :
ADAMTS14 Polyclonal Antibody
products short name :
[ADAMTS14]
products name syn :
[A disintegrin and metalloproteinase with thrombospondin motifs 14,ADAM TS14,ADAMTS 14,ADAMTS14,EC 3.4.24,FLJ32820]
other names :
[A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform 1 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 14; A disintegrin and metalloproteinase with thrombospondin motifs 14; ADAM-TS 14; ADAM-TS14; ADAMTS-14; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 14; metalloprotease-disintegrin protease; ADAM metallopeptidase with thrombospondin type 1 motif, 14]
products gene name :
[ADAMTS14]
other gene names :
[ADAMTS14; ADAMTS14; ADAM-TS 14; ADAM-TS14; ADAMTS-14]
uniprot entry name :
ATS14_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
1226
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:25-1:100
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide of human ADAMTS14
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products categories :
Cell biology
products description :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This gene is highly similar to two family members, ADAMTS2 and ADAMTS3, in its sequence and gene structure, and the encoded protein shares the aminoprocollagen peptidase activity with the protein products encoded by ADAMTS2 and ADAMTS3. Various transcript variants of this gene have been identified. They result from the use of two different promoters and transcription initiation sites as well as alternative splicing sites. The full length nature of some transcripts has not been defined.
ncbi gi num :
110611167
ncbi acc num :
NP_542453
ncbi gb acc num :
NM_139155.2
ncbi pathways :
Collagen Biosynthesis And Modifying Enzymes Pathway (645289); Collagen Formation Pathway (645288); Extracellular Matrix Organization Pathway (576262); Metabolism Of Proteins Pathway (106230); O-glycosylation Of TSR Domain-containing Proteins Pathway (1127680); O-linked Glycosylation Pathway (1127679); Post-translational Protein Modification Pathway (161012)
ncbi summary :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This gene is highly similar to two family members, ADAMTS2 and ADAMTS3, in its sequence and gene structure, and the encoded protein shares the aminoprocollagen peptidase activity with the protein products encoded by ADAMTS2 and ADAMTS3. Various transcript variants of this gene have been identified. They result from the use of two different promoters and transcription initiation sites as well as alternative splicing sites. The full length nature of some transcripts has not been defined. [provided by RefSeq, Jul 2008]
uniprot summary :
ADAMTS14: Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. 4 isoforms of the human protein are produced by alternative promoter. Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; EC 3.4.24.-; Protease. Chromosomal Location of Human Ortholog: 10q21. Cellular Component: proteinaceous extracellular matrix; extracellular region. Molecular Function: zinc ion binding; metalloendopeptidase activity. Biological Process: collagen catabolic process; extracellular matrix organization and biogenesis; collagen fibril organization; proteolysis
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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