SMOC2 Polyclonal Antibody | MyBioSource MBS2527784 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

SMOC2 Polyclonal Antibody

catalog :

MBS2527784

quantity :

0.02 mL

price :

110 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot analysis of Human placenta tissue using SMOC2 Polyclonal Antibody at dilution of 1:250

image 2 :

Immunohistochemistry of paraffin-embedded Human cervical cancer using SMOC2 Polyclonal Antibody at dilution of 1:30

image 3 :

Immunohistochemistry of paraffin-embedded Human liver cancer using SMOC2 Polyclonal Antibody at dilution of 1:30

product information

catalog number :

MBS2527784

products type :

Antibody

products full name :

SMOC2 Polyclonal Antibody

products short name :

[SMOC2]

products name syn :

[DTDP1; SMAP2; MST117; MSTP117; MSTP140; bA37D8.1; bA270C4A.1; dJ421D16.1]

other names :

[SPARC-related modular calcium-binding protein 2 isoform 2; SPARC-related modular calcium-binding protein 2; SPARC-related modular calcium-binding protein 2; SMAP-2; SMOC-2; secreted modular calcium-binding protein 2; smooth muscle associated protein 2; smooth muscle-associated protein 2; thyroglobulin type-1 repeat containing protein; SPARC related modular calcium binding 2; Secreted modular calcium-binding protein 2; SMOC-2; Smooth muscle-associated protein 2; SMAP-2]

products gene name :

[SMOC2]

other gene names :

[SMOC2; SMOC2; DTDP1; SMAP2; MST117; MSTP117; MSTP140; bA37D8.1; bA270C4A.1; dJ421D16.1; SMAP2; SMOC-2; SMAP-2]

uniprot entry name :

SMOC2_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse

sequence length :

446

purity :

Affinity purification

concentration :

0.5mg/mL

storage stability :

Store at -20°C. Avoid freeze/thaw cycles

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB: 1:200-1:1000. IHC: 1:25-1:100

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Immunogen: Synthetic peptide of human SMOC2. Calculated MW: 50kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, PH7.3

products description :

Background: This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains.

ncbi gi num :

262050673

ncbi acc num :

NP_001159884

ncbi gb acc num :

NM_001166412.1

uniprot acc num :

Q9H3U7

ncbi pathways :

Gastric Cancer Network 1 Pathway (760635)

ncbi summary :

This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

uniprot summary :

SMOC2: Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. Defects in SMOC2 are the cause of dentin dysplasia typ1 (DTDP1). A dental defect in which both primary and secondary dentitions are affected. The clinical crowns of both permanent and deciduous teeth are of normal shape, form and color in most cases, although they may be slightly opalescent and blue or brown. Teeth may be very mobile and exfoliate spontaneously because of inadequate root formation. On radiographs, the roots are short and may be more pointed than normal. Pulp chambers are usually absent except for a chevron-shaped remnant in the crown. Root canals are usually absent. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Calcium-binding; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q27. Cellular Component: basement membrane. Molecular Function: heparin binding; calcium ion binding. Biological Process: extracellular matrix organization and biogenesis; signal transduction. Disease: Dentin Dysplasia, Type I

size1 :

0.02 mL

price1 :

110 USD

size2 :

0.06 mL

price2 :

150

size3 :

0.12 mL

price3 :

225

size4 :

0.2 mL

price4 :

360

more info or order :

MyBioSource product webpage