catalog number :
MBS252761
products type :
Recombinant Protein
products full name :
A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12)
products short name :
A Disintegrin And Metalloproteinase With Thrombospondin 12 (ADAMTS12)
other names :
A disintegrin and metalloproteinase with thrombospondin motifs 12 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 12; A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS12; ADAMTS-12; ADAM-TS 12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12; ADAM metallopeptidase with thrombospondin type 1 motif, 12; N/A
products gene name :
ADAMTS12
other gene names :
ADAMTS12; ADAMTS12; PRO4389; ADAM-TS 12; ADAM-TS12; ADAMTS-12
uniprot entry name :
ATS12_HUMAN
sequence :
MGHHHHHHSG SEF- QQMYFWQY GHWTECSVTC GTGIRRQTAH CIKKGRGMVK ATFCDPETQP NGRQKKCHEK ACPPRWWAGE WEACSATCGP HGEKKRTVLC IQTMVSDEQA LPPTDCQHLL KPKTLLSCNR DILCPSDWTV GNWSECSVSC GGGVRIRSVT CAKNHDEPCD VTRKPNSRAL CGLQQCP
other info1 :
Tag Information: N-terminal His-Tag
other info2 :
Organism: Homo sapiens (Human)
ncbi acc num :
NP_112217.2
ncbi gb acc num :
NM_030955.2
ncbi mol weight :
168,460 Da
ncbi pathways :
Metabolism Of Proteins Pathway 106230!!O-glycosylation Of TSR Domain-containing Proteins Pathway 980460!!O-linked Glycosylation Pathway 980459!!Post-translational Protein Modification Pathway 161012
ncbi summary :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq, Jul 2008]