product summary
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company name :
MyBioSource
product type :
antibody
product name :
MAGEA3 Polyclonal Antibody
catalog :
MBS2527540
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of Human testis tissue, A549 and PC3 cell using MAGEA3 Polyclonal Antibody at dilution of 1:400
image 2 :
Immunohistochemistry of paraffin-embedded Human tonsil using MAGEA3 Polyclonal Antibody at dilution of 1:50
image 3 :
Immunohistochemistry of paraffin-embedded Human liver cancer using MAGEA3 Polyclonal Antibody at dilution of 1:50
product information
catalog number :
MBS2527540
products type :
Antibody
products full name :
MAGEA3 Polyclonal Antibody
products short name :
[MAGEA3]
products name syn :
[HIP8; HYPD; CT1.3; MAGE3; MAGEA6]
other names :
[melanoma-associated antigen 3; Melanoma-associated antigen 3; melanoma-associated antigen 3; MAGE-3 antigen; antigen MZ2-D; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3; melanoma antigen family A, 3; melanoma antigen family A3; Antigen MZ2-D; Cancer/testis antigen 1.3; CT1.3; MAGE-3 antigen]
products gene name :
[MAGEA3]
other gene names :
[MAGEA3; MAGEA3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6; MAGE3; CT1.3]
uniprot entry name :
MAGA3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
314
purity :
Affinity purification
storage stability :
Store at -20 degree C (regular). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000. IHC: 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide of human MAGEA3
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. Note: Centrifuge before opening to ensure complete recovery of vial contents.
products categories :
Epigenetics
products description :
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
ncbi gi num :
4885467
ncbi acc num :
NP_005353.1
ncbi gb acc num :
NM_005362.3
uniprot acc num :
P43357
ncbi mol weight :
35kDa
ncbi summary :
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
uniprot summary :
MAGEA3: Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. Protein type: Cancer Testis Antigen (CTA). Chromosomal Location of Human Ortholog: Xq28. Molecular Function: protein binding
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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