catalog number :
MBS2527079
products full name :
IFNA2 Polyclonal Antibody
products short name :
IFNA2
products name syn :
IFNA; INFA2; IFNA2B; IFN-alphaA
other names :
interferon alpha-2; Interferon alpha-2; interferon alpha-2; IFN-alpha-2; alpha-2a interferon; interferon alpha 2a; interferon alpha 2b; interferon alpha A; leIF A; interferon, alpha 2; Interferon alpha-A; LeIF A
products gene name :
IFNA2
other gene names :
IFNA2; IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA; IFNA2A; IFNA2B; IFNA2C; IFN-alpha-2; LeIF A
uniprot entry name :
IFNA2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity purification
storage stability :
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:50-1:200
products description :
Background: This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold.
ncbi acc num :
NP_000596.2
ncbi gb acc num :
NM_000605.3
ncbi pathways :
Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125137); Cytosolic DNA-sensing Pathway (124833); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); Hemostasis Pathway (106028); Hepatitis B Pathway (694606)
ncbi summary :
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
uniprot summary :
IFNA2: Produced by macrophages, IFN-alpha have antiviral activities. Belongs to the alpha/beta interferon family. Protein type: Secreted; Membrane protein, integral; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9p22. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; interferon-alpha/beta receptor binding; cytokine activity. Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; negative regulation of virion penetration into host cell; apoptosis; cytokine and chemokine mediated signaling pathway; innate immune response; inflammatory response; negative regulation of transcription, DNA-dependent; blood coagulation; defense response to virus; negative regulation of T cell differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein