catalog number :
MBS2526843
products full name :
CDC42EP4 Antibody
products short name :
[CDC42EP4]
products name syn :
[BORG4; CEP4; KAIA1777; MGC17125; MGC3740]
other names :
[Cdc42 effector protein 4; Cdc42 effector protein 4; cdc42 effector protein 4; binder of Rho GTPases 4; CDC42 effector protein (Rho GTPase binding) 4; Binder of Rho GTPases 4]
products gene name :
[CDC42EP4]
other gene names :
[CDC42EP4; CDC42EP4; CEP4; BORG4; KAIA1777; BORG4; CEP4]
uniprot entry name :
BORG4_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:500-1:5000
image1 heading :
Testing Data
other info1 :
Immunogen: Fusion protein of CDC42EP4. Calculated Molecular Weight: 38kd. Observed Molecular Weight: 43-45kd
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161471
products description :
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.
uniprot acc num :
BC010451
ncbi summary :
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]
uniprot summary :
CDC42EP4: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts. Belongs to the BORG/CEP family. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q24-q25. Cellular Component: microtubule cytoskeleton; cytoplasm; plasma membrane; endomembrane system; actin cytoskeleton. Molecular Function: GTP-Rho binding. Biological Process: regulation of cell shape; positive regulation of pseudopodium formation; positive regulation of actin filament polymerization; Rho protein signal transduction