product summary
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company name :
MyBioSource
product type :
antibody
product name :
AK1 Polyclonal Antibody
catalog :
MBS2526532
quantity :
0.02 mL
price :
110 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis of Human fetal muscle tissue using AK1 Polyclonal Antibody at dilution of 1:200
product information
catalog number :
MBS2526532
products type :
Antibody
products full name :
AK1 Polyclonal Antibody
products short name :
[AK1]
products name syn :
[HTL-S-58j]
other names :
[adenylate kinase isoenzyme 1; Adenylate kinase isoenzyme 1; adenylate kinase isoenzyme 1; AK 1; AK1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; adenylate monophosphate kinase; myokinase; testis secretory sperm binding protein Li 58j; adenylate kinase 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; Adenylate monophosphate kinase; Myokinase]
products gene name :
[AK1]
other gene names :
[AK1; AK1; HTL-S-58j; ]
uniprot entry name :
KAD1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
194
purity :
Affinity purification
concentration :
1.3mg/mL
storage stability :
Store at -20 degree C.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:200-1:1000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant protein of human AK1. Calculated Molecular Weight: 22kDa
other info2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
products description :
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
ncbi gi num :
4502011
ncbi acc num :
NP_000467.1
ncbi gb acc num :
NM_000476.2
ncbi mol weight :
21,635 Da
ncbi pathways :
Adenine Ribonucleotide Biosynthesis, IMP = ADP,ATP Pathway (618580); Adenine Ribonucleotide Biosynthesis, IMP = ADP,ATP Pathway (468242); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Nucleotides Pathway (106263); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway (161057); Adenosine Ribonucleotides De Novo Biosynthesis Pathway (835389); Purine Nucleotides De Novo Biosynthesis Pathway (142277)
ncbi summary :
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008]
uniprot summary :
AK1: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD). Belongs to the adenylate kinase family. Protein type: EC 2.7.4.6; Nucleotide Metabolism - purine; EC 2.7.4.3; Kinase, other. Chromosomal Location of Human Ortholog: 9q34.1. Cellular Component: cytoplasm; plasma membrane; outer dense fiber; cytosol. Molecular Function: nucleoside diphosphate kinase activity; adenylate kinase activity; ATP binding. Biological Process: ATP metabolic process; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleoside triphosphate biosynthetic process; nucleoside diphosphate phosphorylation; ADP biosynthetic process; AMP metabolic process; cell cycle arrest. Disease: Adenylate Kinase Deficiency, Hemolytic Anemia Due To
size1 :
0.02 mL
price1 :
110 USD
size2 :
0.06 mL
price2 :
150
size3 :
0.12 mL
price3 :
225
size4 :
0.2 mL
price4 :
360
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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