catalog number :
MBS2526359
products full name :
FN3K Antibody
products short name :
FN3K
other names :
fructosamine-3-kinase; Fructosamine-3-kinase; fructosamine-3-kinase; fructosamine 3 kinase
products gene name :
FN3K
other gene names :
FN3K; FN3K
uniprot entry name :
FN3K_HUMAN
reactivity :
Human, Mouse
purity :
Antigen affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:1000-1:10000
other info1 :
Immunogen: Fusion protein of FN3K. Calculated MW: 34kd. Observed MW: 35kd
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
ncbi acc num :
NP_071441.1
ncbi gb acc num :
NM_022158.3
ncbi summary :
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]
uniprot summary :
FN3K: May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme. Belongs to the fructosamine kinase family. Protein type: EC 2.7.1.-; Kinase, other. Chromosomal Location of Human Ortholog: 17q25.3. Molecular Function: fructosamine-3-kinase activity. Biological Process: fructoselysine metabolic process; epithelial cell differentiation; fructosamine metabolic process; phosphorylation