catalog number :
MBS2526243
products full name :
SEMA3G Polyclonal Antibody
products short name :
[SEMA3G]
products name syn :
[sem2]
other names :
[semaphorin-3G; Semaphorin-3G; semaphorin-3G; semaphorin sem2; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G; Semaphorin sem2]
products gene name :
[SEMA3G]
other gene names :
[SEMA3G; SEMA3G; sem2]
uniprot entry name :
SEM3G_HUMAN
purity :
Affinity purification
form :
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
storage stability :
Store at -20 degree C. Avoid freeze/thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
IHC: 1:25-1:100
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant protein of human SEMA3G
products description :
Semaphorins are a class of secreted and membrane proteins that act as axonal growth cone guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric receptor complexes. They are usually cues to deflect axons from inappropriate regions, especially important in neural system development. The major class of proteins that act as their receptors are called plexins. SEMA3G possesses anti-migration and anti-invasion ability. SEMA3G inhibited tumor cell migration and invasion, which may be obtained through cell autonomous or paracrine mechanisms, and SEMA3G is a potential target for antitumor migration and invasion.
ncbi acc num :
NP_064548.1
ncbi gb acc num :
NM_020163.1
uniprot acc num :
BC098137
ncbi pathways :
Axon Guidance Pathway (83065); Axon Guidance Pathway (476)
uniprot summary :
SEMA3G: a secreted protein that has chemorepulsive activities for sympathetic axons. A high-affinity ligand of NRP2. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3p21.1. Cellular Component: membrane. Molecular Function: receptor activity. Biological Process: multicellular organismal development